Vena contracta analysis by color Doppler three‐dimensional transesophageal echocardiography shows geometrical differences between prolapse and pseudoprolapse in eccentric mitral regurgitation

• Published in: Echocardiography (Mount Kisco, N.Y.) N.Y.), 2017-05, Vol.34 (5), p.683-689
• Main Authors: Berdejo, Javier, Shiota, Maiko, Mihara, Hirotsugu, Itabashi, Yuji, Utsunomiya, Hiroto, Shiota, Takahiro
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Algorithms; Echocardiography, Doppler, Color - methods; Echocardiography, Three-Dimensional - methods; Echocardiography, Transesophageal - methods; Female; Humans; Image Enhancement - methods; Image Interpretation, Computer-Assisted - methods; Male; mitral regurgitation; Mitral Valve - diagnostic imaging; Mitral Valve Insufficiency - diagnostic imaging; Mitral Valve Insufficiency - etiology; Mitral Valve Prolapse - complications; Mitral Valve Prolapse - diagnostic imaging; Reproducibility of Results; Sensitivity and Specificity; three‐dimensional echocardiography; vena contracta
• ISSN: 0742-2822; 1540-8175
• DOI: 10.1111/echo.13508

Aims Evaluation of eccentric mitral regurgitation (MR) remains extremely difficult and the role played by its etiology, functional or degenerative, is not well understood. This study aimed to demonstrate the value of three‐dimensional transesophageal echocardiography (3DTEE) in the evaluation of eccentric MR identifying geometric differences in the vena contracta area between functional and degenerative etiologies. Methods and Results We studied 61 patients with eccentric MR (30 functional and 31 degenerative). Regurgitant orifice area was determined by the two‐dimensional proximal isovelocity surface area (2DPISA) and the 3DTEE methods. The ratio between maximum and minimum lengths of the vena contracta was calculated in each patient. Effective regurgitant orifice area by the 2DPISA method was smaller than that estimated by 3DTEE (0.56±0.21 vs 0.72±0.25 cm2). A better correlation between both methods was seen in degenerative mitral regurgitation (DMR; r=.83), with a mean underestimation of 8.2% by the 2DPISA method. A much worse correlation was found in functional mitral regurgitation (FMR; r=.39), where a mean underestimation by the 2DPISA method of 29.1% was observed. There was a more elongated and curved vena contracta in FMR compared to that in DMR (length ratio: 3.4±1.0 vs 2.2±0.7, P