Obesity in the ageing man

Abstract As the population is ageing globally, both ageing and obesity are recognized as major public health challenges. The aim of this narrative review is to present and discuss the current evidence on the changes in body composition, energy balance and endocrine environment that occur in the agei...

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Published in:Metabolism, clinical and experimental clinical and experimental, 2013-10, Vol.62 (10), p.1341-1349
Main Authors: Michalakis, K, Goulis, D.G, Vazaiou, A, Mintziori, G, Polymeris, A, Abrahamian-Michalakis, A
Format: Article
Language:English
Subjects:
ageing
Aging - metabolism
Biological and medical sciences
Body Composition
Endocrinology & Metabolism
Energy Metabolism
Feeding. Feeding behavior
Fundamental and applied biological sciences. Psychology
hormonal changes
Hormones - metabolism
Humans
Male
man
Medical sciences
Metabolic diseases
Obesity
Obesity - metabolism
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:Abstract As the population is ageing globally, both ageing and obesity are recognized as major public health challenges. The aim of this narrative review is to present and discuss the current evidence on the changes in body composition, energy balance and endocrine environment that occur in the ageing man. Obesity in the ageing man is related to changes in both body weight and composition due to alterations in energy intake and total energy expenditure. In addition, somatopenia (decreased GH secretion), late-onset hypogonadism (LOH), changes in thyroid and adrenal function, as well as changes in appetite-related peptides (leptin, ghrelin) and, most importantly, insulin action are related to obesity, abnormal energy balance, redistribution of the adipose tissue and sarcopenia (decreased muscle mass). A better understanding of the complex relationship of ageing-related endocrine changes and obesity could lead to more effective interventions for elderly men.
ISSN:0026-0495
1532-8600
DOI:10.1016/j.metabol.2013.05.019