Loading…
The importance of carotid artery stiffness and increased intima-media thickness in obese children
Atherosclerosis that starts in childhood invariably advances during adulthood. Aim. We aimed to study the effect of obesity on main carotid artery intima-media thickness and arterial stiffness. A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (42 -...
Saved in:
| Published in: | South African medical journal 2012-05, Vol.102 (5), p.295-299 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c561t-3e008e3be8067e27ae4fac308b49c3cbd5a33ceaf2d094ff7b976102d0a9620c3 |
|---|---|
| cites | |
| container_end_page | 299 |
| container_issue | 5 |
| container_start_page | 295 |
| container_title | South African medical journal |
| container_volume | 102 |
| creator | Ozcetin, Mustafa Celikyay, Z Ruken Yuksekkaya Celik, Atac Yilmaz, Resul Yerli, Yasemin Erkorkmaz, Unal |
| description | Atherosclerosis that starts in childhood invariably advances during adulthood. Aim. We aimed to study the effect of obesity on main carotid artery intima-media thickness and arterial stiffness.
A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (42 - group 1) and normal (36 - group 2). All the children were subjected to physical examination, routine biochemical and haematological analysis, carotid ultrasonography and echocardiographic measurements. A detailed medical history was obtained. Body mass index (BMI) was calculated by dividing participants' weight in kilograms by the square of their height in metres. Stiffness index β was calculated using blood pressure and diameter of the systolic and diastolic artery. Intima-media thickness was also measured.
The mean age of the obese and normal (control) groups were 10.12±2.12 years and 9.78±1.78 years respectively. Weight, BMI, and systolic and and diastolic blood pressure values were significantly higher in the obese group (all p |
| doi_str_mv | 10.7196/samj.5351 |
| format | article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1897389030</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A289216452</galeid><sourcerecordid>A289216452</sourcerecordid><originalsourceid>FETCH-LOGICAL-c561t-3e008e3be8067e27ae4fac308b49c3cbd5a33ceaf2d094ff7b976102d0a9620c3</originalsourceid><addsrcrecordid>eNqFkU1LxDAQhnNQ_D74ByQgiJeuSdOmzVEWv0DwoucyTSc2a5usSfaw_96uH-CCIHOYd4bnHYYZQk45m1VcyasI42JWipLvkAOWlzJTZVXsk8MYF2yqSyX3yH4-iUIIeUDguUdqx6UPCZxG6g3VEHyyHYWQMKxpTNYYhzFScB21TgeEiBuV7AjZiJ0Fmnqr3z4h66hvMSLVvR26gO6Y7BoYIp585yPycnvzPL_PHp_uHubXj5kuJU-ZQMZqFC3WTFaYV4CFAS1Y3RZKC912JQihEUzeMVUYU7WqkpxNFSiZMy2OyOXX3GXw7yuMqRlt1DgM4NCvYsNrVYlaMcH-RxnnXAlR5RN6_oW-woCNdcanAHqDN9d5rXIui3JDzf6gpuhwtNo7NHbqbxkufhl6hCH10Q-rZL2L2-DZ96qrdjp1swzT0cO6-fmg-ABoaZkP</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1011193372</pqid></control><display><type>article</type><title>The importance of carotid artery stiffness and increased intima-media thickness in obese children</title><source>Directory of Open Access Journals</source><creator>Ozcetin, Mustafa ; Celikyay, Z Ruken Yuksekkaya ; Celik, Atac ; Yilmaz, Resul ; Yerli, Yasemin ; Erkorkmaz, Unal</creator><creatorcontrib>Ozcetin, Mustafa ; Celikyay, Z Ruken Yuksekkaya ; Celik, Atac ; Yilmaz, Resul ; Yerli, Yasemin ; Erkorkmaz, Unal</creatorcontrib><description>Atherosclerosis that starts in childhood invariably advances during adulthood. Aim. We aimed to study the effect of obesity on main carotid artery intima-media thickness and arterial stiffness.
A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (42 - group 1) and normal (36 - group 2). All the children were subjected to physical examination, routine biochemical and haematological analysis, carotid ultrasonography and echocardiographic measurements. A detailed medical history was obtained. Body mass index (BMI) was calculated by dividing participants' weight in kilograms by the square of their height in metres. Stiffness index β was calculated using blood pressure and diameter of the systolic and diastolic artery. Intima-media thickness was also measured.
The mean age of the obese and normal (control) groups were 10.12±2.12 years and 9.78±1.78 years respectively. Weight, BMI, and systolic and and diastolic blood pressure values were significantly higher in the obese group (all p<0.001). In terms of arterial stiffness and carotid intima-media thickness (CIMT) measurements, all parameters were higher in the obese group than the control (p<0.001). There was a relationship between the degree of obesity and CIMT or stiffness index β. In addition, dilatation and hypertrophy levels in the left ventricle were higher in obese children.
Obese children with risk factors for multiple atherosclerosis could have increased CIMT dimensions and consequently should be screened for these risks. Ultrasonographic CIMT and arterial stiffness measurements can detect vascular damage at an early stage of development in children with cardiovascular risk factors.</description><identifier>ISSN: 0256-9574</identifier><identifier>DOI: 10.7196/samj.5351</identifier><identifier>PMID: 22554336</identifier><language>eng</language><publisher>South Africa: Health & Medical Publishing Group</publisher><subject>Adolescent ; Atherosclerosis ; Body Mass Index ; Cardiovascular Diseases - prevention & control ; Care and treatment ; Carotid Arteries - diagnostic imaging ; Carotid Arteries - pathology ; Carotid artery diseases ; Carotid Intima-Media Thickness ; Case-Control Studies ; Child ; Child Welfare ; Diagnosis ; Female ; Health Status ; Humans ; Male ; Measurement ; Obesity - physiopathology ; Obesity in children ; Risk Factors ; Severity of Illness Index ; South Africa ; Tunica Intima - diagnostic imaging ; Tunica Intima - pathology ; Vascular Resistance</subject><ispartof>South African medical journal, 2012-05, Vol.102 (5), p.295-299</ispartof><rights>COPYRIGHT 2012 Health & Medical Publishing Group</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c561t-3e008e3be8067e27ae4fac308b49c3cbd5a33ceaf2d094ff7b976102d0a9620c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,861,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22554336$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ozcetin, Mustafa</creatorcontrib><creatorcontrib>Celikyay, Z Ruken Yuksekkaya</creatorcontrib><creatorcontrib>Celik, Atac</creatorcontrib><creatorcontrib>Yilmaz, Resul</creatorcontrib><creatorcontrib>Yerli, Yasemin</creatorcontrib><creatorcontrib>Erkorkmaz, Unal</creatorcontrib><title>The importance of carotid artery stiffness and increased intima-media thickness in obese children</title><title>South African medical journal</title><addtitle>S Afr Med J</addtitle><description>Atherosclerosis that starts in childhood invariably advances during adulthood. Aim. We aimed to study the effect of obesity on main carotid artery intima-media thickness and arterial stiffness.
A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (42 - group 1) and normal (36 - group 2). All the children were subjected to physical examination, routine biochemical and haematological analysis, carotid ultrasonography and echocardiographic measurements. A detailed medical history was obtained. Body mass index (BMI) was calculated by dividing participants' weight in kilograms by the square of their height in metres. Stiffness index β was calculated using blood pressure and diameter of the systolic and diastolic artery. Intima-media thickness was also measured.
The mean age of the obese and normal (control) groups were 10.12±2.12 years and 9.78±1.78 years respectively. Weight, BMI, and systolic and and diastolic blood pressure values were significantly higher in the obese group (all p<0.001). In terms of arterial stiffness and carotid intima-media thickness (CIMT) measurements, all parameters were higher in the obese group than the control (p<0.001). There was a relationship between the degree of obesity and CIMT or stiffness index β. In addition, dilatation and hypertrophy levels in the left ventricle were higher in obese children.
Obese children with risk factors for multiple atherosclerosis could have increased CIMT dimensions and consequently should be screened for these risks. Ultrasonographic CIMT and arterial stiffness measurements can detect vascular damage at an early stage of development in children with cardiovascular risk factors.</description><subject>Adolescent</subject><subject>Atherosclerosis</subject><subject>Body Mass Index</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>Care and treatment</subject><subject>Carotid Arteries - diagnostic imaging</subject><subject>Carotid Arteries - pathology</subject><subject>Carotid artery diseases</subject><subject>Carotid Intima-Media Thickness</subject><subject>Case-Control Studies</subject><subject>Child</subject><subject>Child Welfare</subject><subject>Diagnosis</subject><subject>Female</subject><subject>Health Status</subject><subject>Humans</subject><subject>Male</subject><subject>Measurement</subject><subject>Obesity - physiopathology</subject><subject>Obesity in children</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>South Africa</subject><subject>Tunica Intima - diagnostic imaging</subject><subject>Tunica Intima - pathology</subject><subject>Vascular Resistance</subject><issn>0256-9574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqFkU1LxDAQhnNQ_D74ByQgiJeuSdOmzVEWv0DwoucyTSc2a5usSfaw_96uH-CCIHOYd4bnHYYZQk45m1VcyasI42JWipLvkAOWlzJTZVXsk8MYF2yqSyX3yH4-iUIIeUDguUdqx6UPCZxG6g3VEHyyHYWQMKxpTNYYhzFScB21TgeEiBuV7AjZiJ0Fmnqr3z4h66hvMSLVvR26gO6Y7BoYIp585yPycnvzPL_PHp_uHubXj5kuJU-ZQMZqFC3WTFaYV4CFAS1Y3RZKC912JQihEUzeMVUYU7WqkpxNFSiZMy2OyOXX3GXw7yuMqRlt1DgM4NCvYsNrVYlaMcH-RxnnXAlR5RN6_oW-woCNdcanAHqDN9d5rXIui3JDzf6gpuhwtNo7NHbqbxkufhl6hCH10Q-rZL2L2-DZ96qrdjp1swzT0cO6-fmg-ABoaZkP</recordid><startdate>20120501</startdate><enddate>20120501</enddate><creator>Ozcetin, Mustafa</creator><creator>Celikyay, Z Ruken Yuksekkaya</creator><creator>Celik, Atac</creator><creator>Yilmaz, Resul</creator><creator>Yerli, Yasemin</creator><creator>Erkorkmaz, Unal</creator><general>Health & Medical Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>7TS</scope></search><sort><creationdate>20120501</creationdate><title>The importance of carotid artery stiffness and increased intima-media thickness in obese children</title><author>Ozcetin, Mustafa ; Celikyay, Z Ruken Yuksekkaya ; Celik, Atac ; Yilmaz, Resul ; Yerli, Yasemin ; Erkorkmaz, Unal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c561t-3e008e3be8067e27ae4fac308b49c3cbd5a33ceaf2d094ff7b976102d0a9620c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Atherosclerosis</topic><topic>Body Mass Index</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>Care and treatment</topic><topic>Carotid Arteries - diagnostic imaging</topic><topic>Carotid Arteries - pathology</topic><topic>Carotid artery diseases</topic><topic>Carotid Intima-Media Thickness</topic><topic>Case-Control Studies</topic><topic>Child</topic><topic>Child Welfare</topic><topic>Diagnosis</topic><topic>Female</topic><topic>Health Status</topic><topic>Humans</topic><topic>Male</topic><topic>Measurement</topic><topic>Obesity - physiopathology</topic><topic>Obesity in children</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>South Africa</topic><topic>Tunica Intima - diagnostic imaging</topic><topic>Tunica Intima - pathology</topic><topic>Vascular Resistance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ozcetin, Mustafa</creatorcontrib><creatorcontrib>Celikyay, Z Ruken Yuksekkaya</creatorcontrib><creatorcontrib>Celik, Atac</creatorcontrib><creatorcontrib>Yilmaz, Resul</creatorcontrib><creatorcontrib>Yerli, Yasemin</creatorcontrib><creatorcontrib>Erkorkmaz, Unal</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Physical Education Index</collection><jtitle>South African medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ozcetin, Mustafa</au><au>Celikyay, Z Ruken Yuksekkaya</au><au>Celik, Atac</au><au>Yilmaz, Resul</au><au>Yerli, Yasemin</au><au>Erkorkmaz, Unal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The importance of carotid artery stiffness and increased intima-media thickness in obese children</atitle><jtitle>South African medical journal</jtitle><addtitle>S Afr Med J</addtitle><date>2012-05-01</date><risdate>2012</risdate><volume>102</volume><issue>5</issue><spage>295</spage><epage>299</epage><pages>295-299</pages><issn>0256-9574</issn><abstract>Atherosclerosis that starts in childhood invariably advances during adulthood. Aim. We aimed to study the effect of obesity on main carotid artery intima-media thickness and arterial stiffness.
A total of 78 children were studied from October 2010 to February 2011. They were divided into obese (42 - group 1) and normal (36 - group 2). All the children were subjected to physical examination, routine biochemical and haematological analysis, carotid ultrasonography and echocardiographic measurements. A detailed medical history was obtained. Body mass index (BMI) was calculated by dividing participants' weight in kilograms by the square of their height in metres. Stiffness index β was calculated using blood pressure and diameter of the systolic and diastolic artery. Intima-media thickness was also measured.
The mean age of the obese and normal (control) groups were 10.12±2.12 years and 9.78±1.78 years respectively. Weight, BMI, and systolic and and diastolic blood pressure values were significantly higher in the obese group (all p<0.001). In terms of arterial stiffness and carotid intima-media thickness (CIMT) measurements, all parameters were higher in the obese group than the control (p<0.001). There was a relationship between the degree of obesity and CIMT or stiffness index β. In addition, dilatation and hypertrophy levels in the left ventricle were higher in obese children.
Obese children with risk factors for multiple atherosclerosis could have increased CIMT dimensions and consequently should be screened for these risks. Ultrasonographic CIMT and arterial stiffness measurements can detect vascular damage at an early stage of development in children with cardiovascular risk factors.</abstract><cop>South Africa</cop><pub>Health & Medical Publishing Group</pub><pmid>22554336</pmid><doi>10.7196/samj.5351</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0256-9574 |
| ispartof | South African medical journal, 2012-05, Vol.102 (5), p.295-299 |
| issn | 0256-9574 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1897389030 |
| source | Directory of Open Access Journals |
| subjects | Adolescent Atherosclerosis Body Mass Index Cardiovascular Diseases - prevention & control Care and treatment Carotid Arteries - diagnostic imaging Carotid Arteries - pathology Carotid artery diseases Carotid Intima-Media Thickness Case-Control Studies Child Child Welfare Diagnosis Female Health Status Humans Male Measurement Obesity - physiopathology Obesity in children Risk Factors Severity of Illness Index South Africa Tunica Intima - diagnostic imaging Tunica Intima - pathology Vascular Resistance |
| title | The importance of carotid artery stiffness and increased intima-media thickness in obese children |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T23%3A09%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20importance%20of%20carotid%20artery%20stiffness%20and%20increased%20intima-media%20thickness%20in%20obese%20children&rft.jtitle=South%20African%20medical%20journal&rft.au=Ozcetin,%20Mustafa&rft.date=2012-05-01&rft.volume=102&rft.issue=5&rft.spage=295&rft.epage=299&rft.pages=295-299&rft.issn=0256-9574&rft_id=info:doi/10.7196/samj.5351&rft_dat=%3Cgale_proqu%3EA289216452%3C/gale_proqu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c561t-3e008e3be8067e27ae4fac308b49c3cbd5a33ceaf2d094ff7b976102d0a9620c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1011193372&rft_id=info:pmid/22554336&rft_galeid=A289216452&rfr_iscdi=true |