Non‐alcoholic fatty liver and advanced fibrosis in the elderly: Results from a community‐based Polish survey

Background & Aims Development of non‐alcoholic fatty liver (NAFL) is dependent on metabolic factors occurring at an increased frequency with advancing age. Until now, few studies have explored the prevalence of NAFL in aged populations. Our study aimed to determine the prevalence of NAFL and adv...

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Bibliographic Details
Published in:Liver international 2017-11, Vol.37 (11), p.1706-1714
Main Authors: Hartleb, Marek, Barański, Kamil, Zejda, Jan, Chudek, Jerzy, Więcek, Andrzej
Format: Article
Language:English
Subjects:
advanced fibrosis
Age
Age Distribution
Aged
Aged, 80 and over
Alcohols
Biomarkers
Biomarkers - blood
Chronic infection
Community participation
diabetes mellitus
elderly
Fatty liver
Female
Fibrosis
Geriatrics
Humans
Ingestion
Liver
Liver Cirrhosis - epidemiology
Liver diseases
Logistic Models
Male
Multivariate Analysis
Non-alcoholic Fatty Liver Disease - complications
Non-alcoholic Fatty Liver Disease - epidemiology
non‐alcoholic fatty liver
Older people
Poland - epidemiology
Population
Population studies
Prospective Studies
Risk
Risk Factors
Severity of Illness Index
Sex Distribution
Surveys and Questionnaires
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Summary:Background & Aims Development of non‐alcoholic fatty liver (NAFL) is dependent on metabolic factors occurring at an increased frequency with advancing age. Until now, few studies have explored the prevalence of NAFL in aged populations. Our study aimed to determine the prevalence of NAFL and advanced fibrosis in the elderly population participating in a national survey of a community‐based elderly cohort. Methods A total of 3003 participants (mean age 79.6 years, 46.8% male) were enrolled in the study, after applying the following exclusion criteria: individuals younger than 65 years old (n=829) and those with positive serological biomarkers of HBV or HCV infection (n=391), chronic alcohol ingestion (n=727) or incomplete data records (n=745). Based on the fatty liver index (FLI), the participants were classified into three categories: FLI
ISSN:1478-3223
1478-3231
DOI:10.1111/liv.13471