A rare vascular complication in a patient with essential thrombocythaemia: spontaneous abdominal aortic dissection

A 27‐year‐old woman complained of waist and back pain. Abdominal computed tomography angiography showed abdominal aortic dissection, the blood count revealed a high platelet count of 1655 × 109/L. Negative for JAK2V617F, CALR and MPL mutations (i.e. triple‐negative), the patient was diagnosed as ess...

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Bibliographic Details
Published in:Internal medicine journal 2017-05, Vol.47 (5), p.589-592
Main Authors: Chen, Ye, Han, Xue, Wang, Fang, Bai, Beibei, Wang, Yingchun
Format: Article
Language:English
Subjects:
Abdomen
Adult
Aneurysm, Dissecting - diagnostic imaging
Aneurysm, Dissecting - etiology
Aneurysms
Angiography
Aorta
Aortic Aneurysm, Abdominal - diagnostic imaging
Aortic Aneurysm, Abdominal - etiology
Aortic dissection
Computed tomography
essential thrombocythaemia
Female
Humans
myeloproliferative neoplasm
Pain
spontaneous abdominal aortic dissection
therapy
Thrombocythemia, Essential - complications
Thrombocythemia, Essential - diagnostic imaging
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Summary:A 27‐year‐old woman complained of waist and back pain. Abdominal computed tomography angiography showed abdominal aortic dissection, the blood count revealed a high platelet count of 1655 × 109/L. Negative for JAK2V617F, CALR and MPL mutations (i.e. triple‐negative), the patient was diagnosed as essential thrombocythaemia (ET) with abdominal aortic dissection and was treated with cytoreduction and antiplatelet drugs. Cases of abdominal aortic dissection in ET have not been previously reported. As such, we proposed a mechanism of abdominal aortic dissection caused by endothelial dysfunction and further emphasised appropriate management in ET with abdominal aortic dissection.
ISSN:1444-0903
1445-5994
DOI:10.1111/imj.13407