Exudative Retinal Detachment

Abstract Exudative retinal detachment (ERD) develops when fluid collects in the subretinal space. The subretinal space between the photoreceptors and the retinal pigment epithelium is the remnant of the embryonic optic vesicle. In the developed eye the subretinal space is of minimal size, but it can...

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Bibliographic Details
Published in:Survey of ophthalmology 2017-11, Vol.62 (6), p.723-769
Main Authors: Amer, Radgonde, MD, Nalcı, Hilal, MD, Yalçındağ, Nilüfer, MD
Format: Article
Language:English
Subjects:
Angiogenesis Inhibitors - therapeutic use
antiangiogenic factors
bullous retinal detachment
Choroid Diseases - complications
corticosteroids
Diagnosis, Differential
exudative retinal detachment
Humans
Immunosuppressive Agents - therapeutic use
immunosuppressive therapy
Ophthalmology
optical coherence tomography
Retinal Detachment - diagnosis
Retinal Detachment - pathology
Retinal Detachment - therapy
Retinal Pigment Epithelium - pathology
Risk Factors
serous retinal detachment
subretinal space
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Summary:Abstract Exudative retinal detachment (ERD) develops when fluid collects in the subretinal space. The subretinal space between the photoreceptors and the retinal pigment epithelium is the remnant of the embryonic optic vesicle. In the developed eye the subretinal space is of minimal size, but it can re-open under pathological conditions that disrupt the integrity of blood-retinal barrier (BRB). Inflammatory, infectious, infiltrative, neoplastic, vascular and degenerative conditions may be associated with BRB breakdown and the sequential development of ERD. We elaborate on the pathogenesis and the differential diagnosis of ERD and specifically discuss the spectrum of diseases associated with ERD in uveitis clinics.
ISSN:0039-6257
1879-3304
DOI:10.1016/j.survophthal.2017.05.001