Prevalence and Complications of Bicuspid Aortic Valve in Chinese According to Echocardiographic Database

• Published in: The American journal of cardiology 2017-07, Vol.120 (2), p.287-291
• Main Authors: Li, Yijian, MD, Wei, Xin, MD, Zhao, Zhengang, MD, Liao, Yanbiao, MD, He, Jialing, MD, Xiong, Tianyuan, MD, Xu, Yuanning, MD, Lv, Wenyu, MD, Ou, Yuanweixiang, MD, Tang, Hong, MD, Feng, Yuan, MD, Chen, Mao, MD, PhD
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Age groups; Aged; Aged, 80 and over; Aortic valve; Aortic Valve - abnormalities; Aortic Valve Insufficiency - diagnosis; Aortic Valve Insufficiency - epidemiology; Aortic Valve Insufficiency - etiology; Aortic Valve Stenosis - diagnosis; Aortic Valve Stenosis - epidemiology; Aortic Valve Stenosis - etiology; Bicuspid Aortic Valve Disease; Calcification; Cardiology; Cardiovascular; Cardiovascular disease; Child; Child, Preschool; China - epidemiology; Complications; Congenital diseases; Dissection; Echocardiography; Electrocardiography; Endocarditis; Endocarditis - diagnosis; Endocarditis - epidemiology; Endocarditis - etiology; Epidemiology; Female; Follow-Up Studies; Heart; Heart Valve Diseases - complications; Heart Valve Diseases - diagnosis; Heart Valve Diseases - epidemiology; Humans; Incidence; Infant; Infant, Newborn; Male; Middle Aged; Patients; Population studies; Prevalence; Prognosis; Regurgitation; Retrospective Studies; Rheumatic heart disease; Risk Assessment - methods; Risk Factors; Stenosis; Surgery; Womens health; Young Adult
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2017.04.025

Abstract As transcatheter aortic valve replacement (TAVR) has become an alternative treatment for patients at high risk for surgical aortic valve replacement (SAVR), bicuspid aortic valve (BAV) draw our attention again. The reported frequency of BAV was between 0.5% to 2% in western population. However, there was no such epidemiologic study in Chinese population. Our study sought to investigate the prevalence and complications of BAV in China by echocardiographic database. A total of 668 cases who were confirmed with bicuspid aortic valve, identified from 195,708 echocardiographic records of 157,039 patients in the echocardiographic database of West China Hospital (between June 2008 and June 2012), were analyzed retrospectively. The incidence of BAV was 0.43% in the cohort, and 579 (86.68%) patients were complicated by various degree of aortic valve stenosis or aortic valve regurgitation. The incidence of infective endocarditis and aortic dissection was 0.68% episodes per patient-years with mean age of 42.96 ± 11.25 years old and 0.18% episodes per patient-years with mean age of 43.00 ± 5.14 years old, respectively. In conclusion, our study demonstrated that the prevalence of bicuspid aortic valve and complications in Chinese were similar to that in the western population.