LVOT-VTI is a Useful Indicator of Low Ventricular Function in Young Patients

Left ventricular outflow tract velocity time integral (LVOT-VTI), a Doppler-derived measure of stroke distance, is used as a surrogate marker of cardiac function in adults. LVOT-VTI is easily obtained, independent of ventricular geometry and wall motion abnormalities. We investigated the relationshi...

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Bibliographic Details
Published in:Pediatric cardiology 2017-08, Vol.38 (6), p.1148-1154
Main Authors: Navaratnam, Manchula, Punn, Rajesh, Ramamoorthy, Chandra, Tacy, Theresa A.
Format: Article
Language:English
Subjects:
Adolescent
Analysis
Cardiac Surgery
Cardiology
Cardiomyopathy, Dilated - diagnostic imaging
Cardiomyopathy, Dilated - physiopathology
Child
Child, Preschool
Echocardiography, Doppler, Pulsed
Female
Health Status Indicators
Heart
Heart Function Tests
Humans
Infant
Male
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Original Article
Pediatric cardiology
Retrospective Studies
Vascular Surgery
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - physiopathology
Ventricular Function
Young Adult
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Summary:Left ventricular outflow tract velocity time integral (LVOT-VTI), a Doppler-derived measure of stroke distance, is used as a surrogate marker of cardiac function in adults. LVOT-VTI is easily obtained, independent of ventricular geometry and wall motion abnormalities. We investigated the relationship between LVOT-VTI and conventional measures of function in young patients by comparing controls to children with dilated cardiomyopathy (DCM). Sixty-two healthy and 52 DCM patients over 1 year were studied retrospectively. The average pulsed (PW) and continuous wave (CW) LVOT-VTIs from apical views were measured from three cycles. Body surface area (BSA) and Ejection fraction (EF) were obtained. We compared LVOT-VTIs between study and control groups and assessed BSA’s impact on LVOT-VTI. The entire cohort was classified into three levels of LV function which were compared. We determined LVOT-VTI cutoff values that indicated an EF 
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-017-1630-9