Assembly of Self-Cleaning Electrode Surface for the Development of Refreshable Biosensors

Passivation of electrode surface and tedious reconstruction of biosensing architectures have long plagued researchers for the development of electrochemical biosensors. Here, we report a novel self-cleaning electrode by modifying the commonly used working electrode with superhydrophobic and conducti...

Full description

Saved in:
Bibliographic Details
Published in:Analytical chemistry (Washington) 2017-04, Vol.89 (7), p.4131-4138
Main Authors: Zhu, Xiaoli, Chen, Yaoyao, Feng, Chang, Wang, Wei, Bo, Bing, Ren, Ruixin, Li, Genxi
Format: Article
Language:English
Subjects:
Adsorption
Assembly
Biosensing Techniques
Biosensors
Electrochemical Techniques
Electrodes
Molecules
Nanocomposites
Oxidation
Particle Size
Passivation
Reconstruction
Surface chemistry
Surface Properties
Target detection
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Passivation of electrode surface and tedious reconstruction of biosensing architectures have long plagued researchers for the development of electrochemical biosensors. Here, we report a novel self-cleaning electrode by modifying the commonly used working electrode with superhydrophobic and conductive nanocomposite. Owing to the superhydrophobicity and the chemical stability, the electrode avoids passivation result from both adsorption of molecules and oxidation in air. The high conductivity and the high effective area also allow the achievement of enhanced electrochemical signals. On the basis of comprehensive studies on this novel electrode, we have applied it in the fabrication of refreshable electrochemical biosensors for both electro-active and electro-inactive targets. For both cases, detection of the targets can be well performed, and the self-cleaning electrode can be refreshed by simply washing and applied for successive measurements in a long period.
ISSN:0003-2700
1520-6882
DOI:10.1021/acs.analchem.6b05177