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Device and programming abstractions for spatiotemporal control of active micro-particle swarms

We present a hardware setup and a set of executable commands for spatiotemporal programming and interactive control of a swarm of self-propelled microscopic agents inside a microfluidic chip. In particular, local and global spatiotemporal light stimuli are used to direct the motion of ensembles of E...

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Bibliographic Details
Published in:Lab on a chip 2017-04, Vol.17 (8), p.1442-1451
Main Authors: Lam, Amy T, Samuel-Gama, Karina G, Griffin, Jonathan, Loeun, Matthew, Gerber, Lukas C, Hossain, Zahid, Cira, Nate J, Lee, Seung Ah, Riedel-Kruse, Ingmar H
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Language:English
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Summary:We present a hardware setup and a set of executable commands for spatiotemporal programming and interactive control of a swarm of self-propelled microscopic agents inside a microfluidic chip. In particular, local and global spatiotemporal light stimuli are used to direct the motion of ensembles of Euglena gracilis, a unicellular phototactic organism. We develop three levels of programming abstractions (stimulus space, swarm space, and system space) to create a scripting language for directing swarms. We then implement a multi-level proof-of-concept biotic game using these commands to demonstrate their utility. These device and programming concepts will enhance our capabilities for manipulating natural and synthetic swarms, with future applications for on-chip processing, diagnostics, education, and research on collective behaviors.
ISSN:1473-0197
1473-0189
DOI:10.1039/c7lc00131b