Current trends and future perspectives of dental pulp capping materials: A systematic review

To systematically review the literature to analyze the current trends and future perspectives of dental pulp capping materials through an analysis of scientific and technological data. This study is reported in accordance with the PRISMA Statement. Nine databases were screened: PubMed (MedLine), Lil...

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Bibliographic Details
Published in:Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2018-04, Vol.106 (3), p.1358-1368
Main Authors: da Rosa, Wellington L O, Cocco, Alexandra R, Silva, Tiago M da, Mesquita, Luana C, Galarça, Arthur Dias, Silva, Adriana F da, Piva, Evandro
Format: Article
Language:English
Subjects:
Biocompatibility
Biological activity
Biomaterials
Biomedical materials
Calcium
Calcium aluminate
Calcium aluminum silicates
Calcium hydroxide
Calcium phosphates
Capping
Dental materials
Dental pulp
Dental pulp capping
Dental restorative materials
Literature reviews
Materials research
Materials science
Patent applications
Proteins
Resins
Scientific papers
Slaked lime
Trends
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Summary:To systematically review the literature to analyze the current trends and future perspectives of dental pulp capping materials through an analysis of scientific and technological data. This study is reported in accordance with the PRISMA Statement. Nine databases were screened: PubMed (MedLine), Lilacs, IBECS, BBO, Web of Science, Scopus, SciELO, Google Scholar, and The Cochrane Library. Additionally, the following patent applications were searched online in Questel Orbit (Paris, France), USPTO, EPO, JPO, INPI, and Patentscope databases. A total of 716 papers and 83 patents were included. Calcium hydroxide was the main type of material studied, especially for direct pulp capping, followed by MTA. Patents related to adhesives or resins increased from 1998 e 2008, while in the last years, a major increase was observed in bioactive materials (containing bioactive proteins), materials derived from MTA (calcium silicate, calcium phosphate and calcium aluminate-based cements) and MTA. It was possible to obtain a scientific and technological overview of pulp capping materials. MTA has shown favorable results in vital pulp therapy that seem to surpass the disadvantages of calcium hydroxide. Recent advances in bioactive materials and those derived from MTA have shown promising results that could improve biomaterials used in vital pulp treatments. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 1358-1368, 2018.
ISSN:1552-4973
1552-4981
DOI:10.1002/jbm.b.33934