Hemocompatibility of Sulfuric Acid-Treated Metallocene Polyethylene and its Application in Reducing the Quantity of Medical Plastic Waste

The hazards of dumping medical plastics have created a huge demand to reduce the quantity of plastic usage without compromising its quality. The metallocene synthesized polyethylene is one such advent, however, its clinical usage is limited by the problem of hemocompatibility. This study investigate...

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Bibliographic Details
Published in:Polymer-plastics technology and engineering 2017-02, Vol.56 (3), p.240-253
Main Authors: Jaganathan, Saravana Kumar, Balaji, Arunpandian, Mohandas, Hemanth, Sivakumar, Gunalan, Kasi, Palaniappan, M, Selvakumar, Kadiman, Suhaini Bin, Srinivasan, Anandhan, Mohd Faudzi, Ahmad Athif bin, Supriyanto, Eko, Mandal, Mahitosh
Format: Article
Language:English
Subjects:
Adhesion
Biocompatible polymers
blood compatibility
Chemical industry
Clotting
coagulation pathways
Demand
Dumping
Fourier transforms
Infrared analysis
Medical wastes
metallocene polyethylene
Metallocenes
Nanostructure
platelet adhesion
Polyethylene
Polyethylenes
protein adsorption
Roughness
Sulfonic acid
Sulfuric acid
sulfuric acid treatment
Surface chemistry
surface properties
Wettability
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Summary:The hazards of dumping medical plastics have created a huge demand to reduce the quantity of plastic usage without compromising its quality. The metallocene synthesized polyethylene is one such advent, however, its clinical usage is limited by the problem of hemocompatibility. This study investigates the effect of sulfuric acid-induced changes in metallocene polyethylene. Fourier transform infrared spectroscopy analysis illustrated the addition of OH and sulfonic acid group, which subsequently increased the wettability. An improvement in micro as well as nanosurface roughness was observed. Ultimately, the treated surfaces depicted delayed clotting time, adsorption of specific plasma proteins, reduced hemolysis, and resistance against platelet adhesion.
ISSN:0360-2559
1525-6111
DOI:10.1080/03602559.2016.1211696