Fast-spiking, parvalbumin+GABAergic interneurons: From cellular design to microcircuit function

A central player in brain computationA small subgroup of nerve cells plays a central role in information processing in the brain. Hu et al. review our present knowledge about the specific makeup of these neurons. Specifically, the individual properties of the molecules, their distribution within the...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 2014-08, Vol.345 (6196), p.529-529
Main Authors: Hu, Hua, Gan, Jian, Jonas, Peter
Format: Article
Language:English
Subjects:
Anatomy
Brain
Data processing
Information Processing
Inhibition
Mathematical analysis
Mathematical models
Networks
Neurons
Organisms
Principals
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Schizophrenia
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Summary:A central player in brain computationA small subgroup of nerve cells plays a central role in information processing in the brain. Hu et al. review our present knowledge about the specific makeup of these neurons. Specifically, the individual properties of the molecules, their distribution within the cell, and the anatomy of the cells themselves are described. This information helps to explain why these neurons are so important for the function of microcircuits in the brain, as well as the behavior of the organism. This detailed level of understanding will become relevant as these cells become future targets for the treatment of neurological diseases.Science, this issue p. 10.1126/science.1255263
ISSN:0036-8075
1095-9203
DOI:10.1126/science.1255263