Mortality experience among Minnesota taconite mining industry workers

• Published in: Occupational and environmental medicine (London, England) England), 2014-11, Vol.71 (11), p.744-749
• Main Authors: Allen, Elizabeth M, Alexander, Bruce H, MacLehose, Richard F, Ramachandran, Gurumurthy, Mandel, Jeffrey H
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Biological and medical sciences; Cancer; Cardiovascular diseases; Cause of Death; Causes of death; Cohort Studies; Disease; Employment; Female; Heart diseases; Humans; Hypertension - mortality; Iron - adverse effects; Iron compounds; Iron mining; Laboratory animals; Lung cancer; Lung neoplasms; Lung Neoplasms - mortality; Lungs; Male; Medical sciences; Mesothelioma; Mesothelioma - mortality; Middle Aged; Mineralogy; Minerals; Mines; Mining; Mining industries; Mining industry; Minnesota - epidemiology; Mortality; Mortality risk; Myocardial ischemia; Myocardial Ischemia - mortality; Occupational Diseases - mortality; Occupational Exposure - adverse effects; Occupational medicine; Population; Public health. Hygiene-occupational medicine; Quartz; Risk; Silicates - adverse effects; Steel industry; Studies; Taconite; Workers; Workplace; Young Adult
• ISSN: 1351-0711; 1470-7926
• DOI: 10.1136/oemed-2013-102000

Objective To evaluate the mortality experience of Minnesota taconite mining industry workers. Methods Mortality was evaluated between 1960 and 2010 in a cohort of Minnesota taconite mining workers employed by any of the seven companies in operation in 1983. Standardised mortality ratios (SMR) were estimated by comparing observed deaths in the cohort with expected frequencies in the Minnesota population. Standardised rate ratios (SRR) were estimated using an internal analysis to compare mortality by employment duration. Results The cohort included 31 067 workers with at least 1 year of documented employment. Among those, there were 9094 deaths, of which 949 were from lung cancer, and 30 from mesothelioma. Mortality from all causes was greater than expected in the Minnesota population (SMR=1.04, 95% CI 1.02 to 1.04). Mortality from lung cancer and mesothelioma was higher than expected with SMRs of 1.16 for lung cancer (95% CI 1.09 to 1.23) and 2.77 for mesothelioma (95% CI 1.87 to 3.96). Other elevated SMRs included those for cardiovascular disease (SMR=1.10, 95% CI 1.06 to 1.14), specifically for hypertensive heart disease (SMR=1.81, 95% CI 1.39 to 2.33) and ischemic heart disease (SMR=1.11, 95% CI 1.07 to 1.16). Results of the SRR analysis did not show variation in risk by duration of employment. Conclusions This study provides evidence that taconite workers may be at increased risk for mortality from lung cancer, mesothelioma, and some cardiovascular disease. Occupational exposures during taconite mining operations may be associated with these increased risks, but non-occupational exposures may also be important contributors.