In-vitro efficacy of different morphology zinc oxide nanopowders on Streptococcus sobrinus and Streptococcus mutans

ZnO with two different morphologies were used to study the inhibition of Streptococcus sobrinus and Streptococcus mutans which are closely associated with tooth cavity. Rod-like shaped ZnO-A and plate-like shaped ZnO-B were produced using a zinc boiling furnace. The nanopowders were characterized us...

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Bibliographic Details
Published in:Materials Science & Engineering C 2017-09, Vol.78, p.868-877
Main Authors: Mohd Bakhori, Siti Khadijah, Mahmud, Shahrom, Ling, Chuo Ann, Sirelkhatim, Amna Hassan, Hasan, Habsah, Mohamad, Dasmawati, Masudi, Sam'an Malik, Seeni, Azman, Abd Rahman, Rosliza
Format: Article
Language:English
Subjects:
Antibacterial activity
Bacteria
Boiling
Chemical evolution
Crystal defects
Electron microscopy
Energy consumption
Energy transmission
In vitro
Inhibition
Lattice vacancies
Light diffraction
Light scattering
Luminescence
Materials science
Nanostructures - chemistry
Particle physics
Photoluminescence
Photon correlation spectroscopy
Photons
Plates (structural members)
Polycrystals
Raman spectroscopy
Reactive oxygen species
Spectroscopy
Streptococcus
Streptococcus infections
Streptococcus mutans
Streptococcus sobrinus
Teeth
Transmission electron microscopy
Wurtzite
X-Ray Diffraction
Zinc
Zinc Oxide
Zinc oxides
ZnO nanopowder
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Summary:ZnO with two different morphologies were used to study the inhibition of Streptococcus sobrinus and Streptococcus mutans which are closely associated with tooth cavity. Rod-like shaped ZnO-A and plate-like shaped ZnO-B were produced using a zinc boiling furnace. The nanopowders were characterized using energy filtered transmission electron microscopy (EFTEM), X-ray diffraction (XRD), photoluminescence (PL) spectroscopy, Raman spectroscopy and dynamic light scattering (DLS) to confirm the properties of the ZnO polycrystalline wurtzite structures. XRD results show that the calculated crystallite sizes of ZnO-A and ZnO-B were 36.6 and 39.4nm, respectively, whereas DLS revealed particle size distributions of 21.82nm (ZnO-A) and 52.21nm (ZnO-B). PL spectra showed ion vacancy defects related to green and red luminescence for both ZnO particles. These defects evolved during the generation of reactive oxygen species which contributed to the antibacterial activity. Antibacterial activity was investigated using microdilution technique towards S. sobrinus and S. mutans at different nanopowder concentrations. Results showed that ZnO-A exhibited higher inhibition on both bacteria compared with ZnO-B. Moreover, S. mutans was more sensitive compared with S. sobrinus because of its higher inhibition rate. •Effect of different morphology of ZnO nanostructure towards Streptococcus sobrinus and Streptococcus mutans•The relation between ZnO properties (optical, structural and morphological) on antibacterial activity of ZnO•Smaller particle size of ZnO revealed by EFTEM, XRD and DLS give higher inhibition on bacteria•Defects of ion vacancy detected by photoluminescence spectroscopy influenced the antibacterial activity of ZnO
ISSN:0928-4931
1873-0191
DOI:10.1016/j.msec.2017.04.085