Duodenal Gangliocytic Paraganglioma: Endoscopy, Sonography and F-18 FDG PET/CT imaging

Abstract We report a case of duodenal gangliocytic paraganglioma (GP). Duodenal GP is a rare subepithelial lesion that typically arises from the region of the major duodenal papilla. It is the third most common duodenal neuroendocrine tumor (NET), after gastrinoma and somatostatinoma. According to t...

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Bibliographic Details
Published in:Digestive and liver disease 2017-10, Vol.49 (10), p.1162-1162
Main Authors: Yang, Ming, Leighton, Jonathan A, Faigel, Douglas O, Katariya, Nitin N
Format: Article
Language:English
Subjects:
Duodenal Neoplasms - diagnostic imaging
Duodenal Neoplasms - pathology
Duodenal Neoplasms - surgery
Duodenum - pathology
Endoscopy
Fluorodeoxyglucose F18
Gastroenterology and Hepatology
Humans
Laparotomy
Male
Middle Aged
Paraganglioma - diagnostic imaging
Paraganglioma - pathology
Paraganglioma - surgery
Positron Emission Tomography Computed Tomography
Ultrasonography
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Summary:Abstract We report a case of duodenal gangliocytic paraganglioma (GP). Duodenal GP is a rare subepithelial lesion that typically arises from the region of the major duodenal papilla. It is the third most common duodenal neuroendocrine tumor (NET), after gastrinoma and somatostatinoma. According to the World Health Organization classification, duodenal GP is considered a benign lesion, even though occasionally it may exhibit regional lymph node metastasis. Its clinical manifestations include gastrointestinal bleeding, abdominal pain and anemia. Histopathologically, it features specific triphasic cellular differentiation and immunohistological stain (IHS) patterns.
ISSN:1590-8658
1878-3562
DOI:10.1016/j.dld.2017.05.006