An Examination of Stroke Risk and Burden in South Asians

Background South Asians (India, Pakistan, Sri Lanka, Bangladesh, Nepal, and Bhutan) are at a disproportionately higher risk of stroke and heart disease due to their cardiometabolic profile. Despite evidence for a strong association between diabetes and stroke, and growing stroke risk in this ethnic...

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Published in:Journal of stroke and cerebrovascular diseases 2017-10, Vol.26 (10), p.2145-2153
Main Authors: Singh, Vineeta, MD, Prabhakaran, Shyam, MD, Chaturvedi, Seemant, MD, Singhal, Aneesh, MD, Pandian, Jeyaraj, MD, DM
Format: Article
Language:English
Subjects:
Aged
Asia, Western - ethnology
Asian Continental Ancestry Group
Cardiovascular
Emigrants and Immigrants
Emigration and Immigration
epidemiology
Europe - epidemiology
Female
Humans
immigrants
Incidence
Male
Middle Aged
Neurology
North America - epidemiology
Prevalence
race and ethnicity
Risk Assessment
Risk Factors
South Asians
special populations
Stroke
Stroke - diagnosis
Stroke - ethnology
Stroke - mortality
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Summary:Background South Asians (India, Pakistan, Sri Lanka, Bangladesh, Nepal, and Bhutan) are at a disproportionately higher risk of stroke and heart disease due to their cardiometabolic profile. Despite evidence for a strong association between diabetes and stroke, and growing stroke risk in this ethnic minority—notwithstanding reports of higher stroke mortality irrespective of country of residence—the explanation for the excess risk of stroke remains unknown. Methods We have used extensive literature review, epidemiologic studies, morbidity and mortality records, and expert opinions to examine the burden of stroke among South Asians, and the risk factors identified thus far. Results We summarize existing evidence and indicate gaps in current knowledge of stroke epidemiology among South Asian natives and immigrants. Conclusions This research focuses attention on a looming epidemic of stroke mainly due to modifiable risk factors, but also new determinants that might aggravate the effect of vascular risk factors in South Asians causing more disabling strokes and death.
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2017.04.036