Impact of prenatal exposure to polycyclic aromatic hydrocarbons from maternal diet on birth outcomes: a birth cohort study in Korea

Polycyclic aromatic hydrocarbons (PAH) are common dietary exposures that cross the human placenta and are classified as a probable human carcinogen. The aim of the present study was to investigate the potential impact of exposure to PAH-containing meat consumed during pregnancy on birth outcomes. Pr...

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Bibliographic Details
Published in:Public health nutrition 2016-10, Vol.19 (14), p.2562-2571
Main Authors: Lamichhane, Dirga Kumar, Leem, Jong-Han, Kim, Hwan-Cheol, Lee, Ji-Young, Park, Myung-Sook, Jung, Dal-Young, Ko, Jung Keun, Ha, Mina, Kim, Yangho, Hong, Yun-Chul, Ha, Eun-Hee
Format: Article
Language:English
Subjects:
Beef
Birth Weight
Cohort analysis
Cooking
Curing
Diet
Environmental health
Epidemiology
Female
Fetuses
Gestational age
High temperature
Humans
Hypertension
Infant, Newborn
Meat
Metabolites
Missing data
Mothers
Multiple births
Nutritional epidemiology
Polycyclic aromatic hydrocarbons
Polycyclic Aromatic Hydrocarbons - adverse effects
Pregnancy
Prenatal exposure
Prenatal Exposure Delayed Effects - epidemiology
Prospective Studies
Republic of Korea - epidemiology
Research Papers
Urine
Womens health
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Summary:Polycyclic aromatic hydrocarbons (PAH) are common dietary exposures that cross the human placenta and are classified as a probable human carcinogen. The aim of the present study was to investigate the potential impact of exposure to PAH-containing meat consumed during pregnancy on birth outcomes. Prospective birth cohort study. Only non-smoking women with singleton pregnancies, who were free from chronic disease such as diabetes and hypertension, were included in the study. Maternal consumption of PAH-rich meat was estimated through FFQ. Multiple linear regression was used to assess factors related to higher intake and the association between dietary PAH and birth outcomes. Republic of Korea, 2006-2011. Pregnant women (n 778) at 12-28 weeks of gestation enrolled in the Mothers and Children's Environmental Health (MOCEH) study. The multivariable regression model showed a significant reduction in birth weight associated with higher consumption level of foods rich in PAH, such as grilled or roasted meat, during pregnancy (β=-17·48 g, P
ISSN:1368-9800
1475-2727
DOI:10.1017/S1368980016000550