Early response evaluation using CT-perfusion one day after transarterial chemoembolization for HCC predicts treatment response and long-term disease control

Highlights • CT perfusion can predict response to TACE within one day after treatment. • This response is sustained during long-term follow up. • Treatment related decisions, e.g. retreatment, can now be made within one day of therapy.

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Bibliographic Details
Published in:European journal of radiology 2017-05, Vol.90, p.73-80
Main Authors: Tamandl, Dietmar, Waneck, Fredrik, Sieghart, Wolfgang, Unterhumer, Sylvia, Kölblinger, Claus, Baltzer, Pascal, Ba-Ssalamah, Ahmed, Loewe, Christian
Format: Article
Language:English
Subjects:
Blood Volume
Carcinoma, Hepatocellular - diagnostic imaging
Carcinoma, Hepatocellular - pathology
Chemoembolization
Chemoembolization, Therapeutic - methods
Chemoembolization, Therapeutic - standards
Computed tomography
Hepatocellular carcinoma
Humans
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - pathology
Neoplasm Recurrence, Local
Perfusion
Radiology
Response assessment
Sensitivity and Specificity
Tomography, X-Ray Computed - methods
Treatment Outcome
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Description
Summary:Highlights • CT perfusion can predict response to TACE within one day after treatment. • This response is sustained during long-term follow up. • Treatment related decisions, e.g. retreatment, can now be made within one day of therapy.
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2017.02.032