Incidence and prognosis of carcinoid syndrome: hormones or tumour burden?

When increased, urinary 5-HIAA excretion is associated with a shorter survival, but adjusment for tumour burden corrects for this fact once more.2,5 This does not mean that the effect of carcinoid syndrome should be underestimated: flushing and diarrhoea have severe effects on quality of life in pat...

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Bibliographic Details
Published in:The lancet oncology 2017-06, Vol.18 (6), p.e299-e299
Main Authors: Zandee, Wouter T, de Herder, Wouter W, Jann, Henning
Format: Article
Language:English
Subjects:
Carcinoid Tumor
Coronary artery disease
Diarrhea
Excretion
Heart diseases
Hematology, Oncology and Palliative Medicine
Humans
Incidence
Malignant Carcinoid Syndrome
Medical prognosis
Metastasis
Prognosis
Quality of life
Studies
Tumor Burden
Tumors
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Summary:When increased, urinary 5-HIAA excretion is associated with a shorter survival, but adjusment for tumour burden corrects for this fact once more.2,5 This does not mean that the effect of carcinoid syndrome should be underestimated: flushing and diarrhoea have severe effects on quality of life in patients, and carcinoid heart disease has high mortality if left untreated. HJ reports grants from European Neuroendocrine Tumor Society (ENETS) outside of the submitted work. 1 DM Halperin, C...
ISSN:1470-2045
1474-5488
DOI:10.1016/S1470-2045(17)30335-2