The newly emerging duck-origin goose parvovirus in China exhibits a wide range of pathogenicity to main domesticated waterfowl

• Published in: Veterinary microbiology 2017-05, Vol.203, p.252-256
• Main Authors: Xiao, Shifeng, Chen, Shilong, Cheng, Xiaoxia, Lin, Fengqiang, Wang, Shao, Zhu, Xiaoli, Yu, Bo, Huang, Meiqing, Wang, Jinxiang, Wu, Nanyang, Zheng, Min, Chen, Shaoying, Yu, Fusong
• Format: Article
• Language: English
• Subjects: Animals; Anorexia; Anseriformes; Antibodies; Antigens; Aquatic birds; Beaks; Bird Diseases - epidemiology; Bird Diseases - virology; Birds; Diarrhea; Distinct duck-origin goose parvovirus; Ducks - virology; Dwarfism; Goslings; Growth rate; Intestine; Juveniles; Kidneys; Lesions; Liver; Muscovy ducklings; Pancreas; Parvovirinae - isolation & purification; Parvovirinae - pathogenicity; Parvoviruses; Pathogenicity; Pathogens; Pathology; Sheldrake ducklings; Short beak and dwarfism syndrome; Spleen; Tissues; Valleys; Viral Load; Virulence; Viruses; Wildfowl
• ISSN: 0378-1135; 1873-2542
• DOI: 10.1016/j.vetmic.2017.03.012

•Short beak and dwarfism syndrome virus (SBDSV) is a newly emerging distinct duck-origin goose parvovirus that belongs to the genus Dependovirus.•The pathogenicity of SBDSV was evaluated in domesticated waterfowl including Muscovy ducklings, Sheldrake ducklings and domestic goslings.•SBDSV exhibits a wide range of pathogenicity to main domesticated waterfowl with variable symptoms. Short beak and dwarfism syndrome virus (SBDSV) is a newly emerging distinct duck-origin goose parvovirus that belongs to the genus Dependovirus. Our previous studies have found that SBDSV was highly pathogenic to Cherry Valley ducklings and mule ducklings. However, little is known about its pathogenicity to other waterfowls. In the present study, the pathogenicity of SBDSV was evaluated in domesticated waterfowl including Muscovy ducklings, Sheldrake ducklings and domestic goslings. All experimentally infected birds exhibited remarkable growth retardation, anorexia and diarrhea similar to naturally infected birds. Interestingly, atrophic beaks and protruded tongues were not observed in all infection groups. At necropsies, no diagnostic pathological lesions were observed. Viral antigens existed in most organ tissues such as heart, liver, spleen, kidney, pancreas and intestine. All ducks in Muscovy duckling and Sheldrake duckling infected groups and 70% goslings in infected groups were seropositive for goose parvovirus (GPV) antibodies at 21dpi with the average titers as 28.4, 26.9, 24.0, respectively. Muscovy ducklings were more prominent in viral load and weight loss with a higher GPV antibodies titer than Sheldrake ducklings and goslings. Taken together, SBDSV exhibits a wide range of pathogenicity to main domesticated waterfowl with variable symptoms and cause considerable economic losses in China.