Prevalence of non-infectious comorbidities in the HIV-positive population in Belgium: a multicenter, retrospective study

Objectives: In Belgium, eleven AIDS Reference Centers (ARCs) and seven AIDS Reference Laboratories diagnose and treat HIV-positive individuals and track patients under care. As AIDS-related deaths are avoided and the HIV-positive population ages, non-infectious comorbidities (NICMs), such as cardiov...

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Bibliographic Details
Published in:Acta clinica belgica (English ed. Online) 2018-01, Vol.73 (1), p.50-53
Main Authors: Gunter, Jessie, Callens, Steven, De Wit, Stephane, Goffard, Jean-Christophe, Moutschen, Michel, Darcis, Gilles, Meuris, Christelle, van den Bulcke, Charlotte, Fombellida, Karine, del Forge, Marc, Razavi, Homie, Wyndham-Thomas, Chloe
Format: Article
Language:English
Subjects:
Adult
AIDS
Belgium
Belgium - epidemiology
cohort studies
Comorbidity
Female
HIV
HIV Infections - mortality
Human health sciences
Humans
Immunologie & maladie infectieuse
Immunology & infectious disease
Male
Middle Aged
non-infectious comorbidities
Prevalence
Retrospective Studies
Sciences de la santé humaine
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Summary:Objectives: In Belgium, eleven AIDS Reference Centers (ARCs) and seven AIDS Reference Laboratories diagnose and treat HIV-positive individuals and track patients under care. As AIDS-related deaths are avoided and the HIV-positive population ages, non-infectious comorbidities (NICMs), such as cardiovascular disease, renal disease and certain cancers, play a larger role in the quality and length of patients' lives. This study aims to characterize the HIV-positive population in Belgium in terms of the prevalence of key NICMs. Methods: We performed a retrospective study of 5787 HIV-positive patients under follow-up at four ARCs across Belgium between 1st of June 2014 and 1st of July 2016. Results: The mean age of patients under follow-up was 46.7 (SD = 11.6) years, and the mean nadir CD4 count was 268.8 cells/mm 3 (SD = 189.5). The prevalence of diabetes mellitus, arterial hypertension and chronic kidney disease (CKD) were 5.9, 31 and 7.8%, respectively. Cardiovascular events, defined as the occurrence of myocardial infarction, stroke or an invasive coronary procedure, occurred in 2.9% of patients. The highest age-adjusted mortality rates were observed among patients 51-55 years of age. Mortality rates were also higher among patients with CKD and patients with viremic hepatitis C virus (p 
ISSN:1784-3286
2295-3337
2295-3337
DOI:10.1080/17843286.2017.1339965