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A retrospective analysis of the effect of human milk on prevention of necrotizing enterocolitis and postnatal growth

Objective: The objective of this study is to determine whether the use of donor human milk (DHM) in very low birth weight (VLBW, ⩽1500 g) neonates in a large neonatal intensive care unit (NICU) affected the rate of necrotizing enterocolitis (NEC) or impacted growth. Study Design: This was a retrospe...

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Bibliographic Details
Published in:Journal of perinatology 2016-03, Vol.36 (3), p.221-224
Main Authors: Chowning, R, Radmacher, P, Lewis, S, Serke, L, Pettit, N, Adamkin, D H
Format: Article
Language:English
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Summary:Objective: The objective of this study is to determine whether the use of donor human milk (DHM) in very low birth weight (VLBW, ⩽1500 g) neonates in a large neonatal intensive care unit (NICU) affected the rate of necrotizing enterocolitis (NEC) or impacted growth. Study Design: This was a retrospective chart review of 550 VLBW neonates following the introduction of DHM as the preferred diet if maternal breast milk (MBM) was not available. Demographics, growth parameters, incidence of NEC or death and days of DHM or MBM were extracted from charts. Result: Compared with infants who received human milk (HM) on fewer than 50% of hospital days, neonates who received HM on ⩾50% of hospital days had equivalent growth outcomes but lower rates of NEC (NEC 3.4 vs 13.5%, P
ISSN:0743-8346
1476-5543
DOI:10.1038/jp.2015.179