P225Insulin-like growth factor-i of children with coeliac disease having protein-energetic insufficiency

• Published in: Archives of disease in childhood 2017-06, Vol.102 (Suppl 2), p.A120-A120
• Main Authors: Klimov, Leonid, Zakharova, Irina, Stoyan, Marina, Kuryaninova, Victoria, Atanesyan, Roza, Gerasimenko, Elena
• Format: Article
• Language: English
• ISSN: 0003-9888
• DOI: 10.1136/archdischild-2017-313273.313

Background and aimsthe IGF-I data analysis of children with coeliac disease (CD), keeping to the gluten-free diet (GFD) against the background of supplementation of the ration with hypercaloric mixture.Materials and methodsThe IGF-I level analysis of 22 children with CD (8 boys and 14 girls) at the age of from 2 till 10 who kept to the strict GFD during not less then a year was conducted. Depending on the type of protein-energetic insufficiency, the patients were divided into 3 groups: the first group consists of 8 (36,4%) children with acute protein-energetic insufficiency, the second one consists of 9 (40,9%) children with chronic protein-energetic insufficiency, the third group is a group of 5 (22,7%) patients without protein-energetic insufficiency. During 1 month children were getting 200 ml of hypercaloric mixture in addition to their ration. The test group consisted of 30 healthy children at the age of from 2 till 10. The research of IGF-I of children with CD was conducted twice-before and after the course of ration enrichment.Results and discussionThe level of IGF-I in the test group is (X plus or minus m) 141,8 plus or minus 11,1 mg/l, the level of IGF-I of patients with CD against the background of the GFD is 98,0 plus or minus 9,6 mk/n; (p