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Pulmonary Vein Doppler Patterns in Infants with Single Right Ventricle Anomalies After Initial Staged Palliations

The aim of this study was to describe serial changes in echocardiographic Doppler pulmonary vein flow (PVF) patterns in infants with single right ventricle (RV) anomalies enrolled in the Single Ventricle Reconstruction trial. Measurement of PVF peak systolic (S) and diastolic (D) velocities, velocit...

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Published in:Pediatric cardiology 2017-08, Vol.38 (6), p.1288-1295
Main Authors: Kirkpatrick, Edward C., Steltzer, Jessica, Simpson, Pippa, Pan, Amy, Dragulescu, Andrea, Falkensammer, Christine B., Gelehrter, Sarah, Lai, Wyman W., Levine, Jami, Miller, Stephen, Miller, Thomas A., Pruetz, Jay, Sachdeva, Ritu, Thacker, Deepika, Frommelt, Peter
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Language:English
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Summary:The aim of this study was to describe serial changes in echocardiographic Doppler pulmonary vein flow (PVF) patterns in infants with single right ventricle (RV) anomalies enrolled in the Single Ventricle Reconstruction trial. Measurement of PVF peak systolic (S) and diastolic (D) velocities, velocity time integrals (VTI), S/D peak velocity and VTI ratios, and frequency of atrial reversal (Ar) waves were made at three postoperative time points in 261 infants: early post-Norwood, pre-stage II surgery, and 14 months. Indices were compared over time, between initial shunt type [modified Blalock–Taussig shunt (MBTS) and right ventricle-to-pulmonary artery shunt (RVPAS)] and in relation to clinical outcomes. S velocities and VTI increased over time while D wave was stable, resulting in increasing S/D peak velocity and VTI ratios, with a median post-Norwood S/D VTI ratio of 1.14 versus 1.38 at pre-stage II and 1.89 at 14 months ( P  
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-017-1660-3