Burned-out seminoma revealed by solitary rib bone metastasis

Burned-out tumor is a rare phenomenon in which a testicular tumor regresses in the primary lesion and progresses in a metastatic lesion. We report the case of a 30-year-old male with burned-out seminoma revealed by open biopsy of solitary 10th rib bone metastasis. He underwent inguinal orchiectomy,...

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Bibliographic Details
Published in:Skeletal radiology 2017-10, Vol.46 (10), p.1415-1420
Main Authors: Nishisho, Toshihiko, Sakaki, Mika, Miyagi, Ryo, Takao, Shoichiro, Sairyo, Koichi
Format: Article
Language:English
Subjects:
Adult
Antineoplastic Combined Chemotherapy Protocols
Biopsy
Bleomycin
Bleomycin - administration & dosage
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - secondary
Bone Neoplasms - surgery
Cancer
Case Report
Chemotherapy
Cisplatin
Cisplatin - administration & dosage
Combined Modality Therapy
Contrast Media
Diagnosis, Differential
Etoposide
Etoposide - administration & dosage
Humans
Imaging
Magnetic Resonance Imaging
Male
Medicine
Medicine & Public Health
Metastases
Metastasis
Nuclear Medicine
Orchiectomy
Orthopedics
Pathology
Radiology
Rib
Rib cage
Ribs - diagnostic imaging
Ribs - pathology
Ribs - surgery
Seminoma
Seminoma - diagnostic imaging
Seminoma - drug therapy
Seminoma - secondary
Seminoma - surgery
Testes
Testicular cancer
Testicular Neoplasms - drug therapy
Testicular Neoplasms - pathology
Testicular Neoplasms - surgery
Tomography, X-Ray Computed
Tumors
Vincristine
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Summary:Burned-out tumor is a rare phenomenon in which a testicular tumor regresses in the primary lesion and progresses in a metastatic lesion. We report the case of a 30-year-old male with burned-out seminoma revealed by open biopsy of solitary 10th rib bone metastasis. He underwent inguinal orchiectomy, which revealed hyalinization, indicating a spontaneously regressed testicular tumor. Chemotherapy for seminoma was administered in three cycles of bleomycin + etoposide + cisplatin therapy. The chemotherapy was effective, and wide resection of the rib was subsequently performed. No postoperative chemotherapy was performed, and there has been no evidence of recurrence for 3 years postoperatively.
ISSN:0364-2348
1432-2161
DOI:10.1007/s00256-017-2701-y