The incidence of the nephrotic syndrome in childhood in Germany

Background The incidence of childhood nephrotic syndrome (NS) in Germany is not well known. Methods An ESPED-based nationwide collection of epidemiological data of children in 2005 and 2006. Result The mean age of NS at onset was 5.5 ± 3.7 years. The gender ratio of boys to girls was 1.8:1. The aver...

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Bibliographic Details
Published in:Clinical and experimental nephrology 2018-02, Vol.22 (1), p.126-132
Main Authors: Franke, Ingo, Aydin, Malik, Llamas Lopez, Corinna Elke, Kurylowicz, Lisa, Ganschow, Rainer, Lentze, Michael, Born, Mark
Format: Article
Language:English
Subjects:
Childhood
Children
Epidemiology
Kidney diseases
Medicine
Medicine & Public Health
Nephrology
Nephrotic syndrome
Original Article
Urology
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Summary:Background The incidence of childhood nephrotic syndrome (NS) in Germany is not well known. Methods An ESPED-based nationwide collection of epidemiological data of children in 2005 and 2006. Result The mean age of NS at onset was 5.5 ± 3.7 years. The gender ratio of boys to girls was 1.8:1. The average length of stay was 15.5 ± 11.2 days, with younger children remaining significantly longer in hospital. Steroid-resistance was more common in children ≥8 years ( p  = 0.023). Focal-segmental glomerulosclerosis (FSGS) was more common in children >10 years ( p  = 0.029). The ratio of males to females with FSGS was 1:1.9, thus the FSGS risk for girls at onset was 3.3-times greater. Considering the available data, the incidence of NS in Germany is 1.2/100,000 in the population
ISSN:1342-1751
1437-7799
DOI:10.1007/s10157-017-1433-6