Sclerosing odontogenic carcinoma: current diagnostic and management considerations concerning a most unusual neoplasm

Abstract Sclerosing odontogenic carcinoma (SOC) is a primary intraosseous carcinoma of the jaws that has been listed as a separate entity for the first time in the latest version of the World Health Organization classification of Head and Neck Tumours (2017). The aim of this study was to analyse and...

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Bibliographic Details
Published in:International journal of oral and maxillofacial surgery 2017-12, Vol.46 (12), p.1641-1649
Main Authors: Hanisch, M, Baumhoer, D, Elges, S, Fröhlich, L.F, Kleinheinz, J, Jung, S
Format: Article
Language:English
Subjects:
Carcinoma - diagnostic imaging
Carcinoma - pathology
Carcinoma - surgery
Dentistry
Head and Neck Neoplasms - diagnostic imaging
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - surgery
Humans
immunohistochemistry
Odontogenic Tumors - diagnostic imaging
Odontogenic Tumors - pathology
Odontogenic Tumors - surgery
odontogenic tumour
oral oncology
sclerosing odontogenic carcinoma
Surgery
WHO Classification of Head and Neck Tumours 2017
World Health Organization
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Summary:Abstract Sclerosing odontogenic carcinoma (SOC) is a primary intraosseous carcinoma of the jaws that has been listed as a separate entity for the first time in the latest version of the World Health Organization classification of Head and Neck Tumours (2017). The aim of this study was to analyse and interpret the existing literature on SOC in the context of a clinical case treated in the authors’ department. A systematic search of the PubMed database was performed in accordance with the PRISMA guidelines, yielding nine cases of SOC reported so far. In summary, characteristic clinical and radiological features of SOC include asymptomatic swelling, location predominantly in the mandible, tumour primarily lytic in appearance, presence of cortical bone destruction, and lack of metastatic spread. Due to the rarity of the disease, close collaboration between oral/maxillofacial surgeons and pathologists is crucial to avoid misdiagnosis. With complete excision, no recurrence of SOC should be expected.
ISSN:0901-5027
1399-0020
DOI:10.1016/j.ijom.2017.05.024