Analgesic, anti-inflammatory and antipyretic activity of Salvia moorcroftiana

Salvia moorcroftiana is an herbaceous plant commonly known as "Kallijari" in Pakistan and belongs to the family Lamiaceae. This study was carried out to evaluate its scientific base for its traditional use in pain, fever and inflammation. The powdered plant was extracted by the method of c...

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Bibliographic Details
Published in:Pakistan journal of pharmaceutical sciences 2017-03, Vol.30 (2), p.481-486
Main Authors: Hussain, Liaqat, Akash, Muhammad Sajid Hamid, Ain, Noorul, Qadir, Muhammad Imran
Format: Article
Language:English
Subjects:
Analgesics - pharmacology
Animals
Anti-Inflammatory Agents - pharmacology
Antipyretics - pharmacology
Carrageenan
Dose-Response Relationship, Drug
Edema - chemically induced
Edema - prevention & control
Fever - chemically induced
Fever - prevention & control
Health aspects
Mice
Pain Measurement - drug effects
Pharmaceutical research
Phytochemicals - analysis
Plant biochemistry
Plant extracts
Plant Extracts - pharmacology
Plant Extracts - toxicity
Saccharomyces cerevisiae
Salvia
Salvia - chemistry
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Summary:Salvia moorcroftiana is an herbaceous plant commonly known as "Kallijari" in Pakistan and belongs to the family Lamiaceae. This study was carried out to evaluate its scientific base for its traditional use in pain, fever and inflammation. The powdered plant was extracted by the method of cold maceration using aqueous methanol (70:30) as solvents. Hot plate, flick tail and acetic acid induced writhing test were utilized for analgesic assessment. Anti-inflammatory activity was evaluated by carageenan-induced mice paw edema. Brewer's induced pyrexia was used for the evaluation of antipyretic activity. Non-significant (p
ISSN:1011-601X