Botulinum toxin A injections in neuropathic pain : A post-hoc subgroup analysis of patients with peripheral nerve injury

The randomized controlled trial (RCT) presented in this article showed significant relief in neuropathic pain following subcutaneous injections of botulinum toxin A over 24 weeks compared to placebo. This result was confirmed in a novel post-hoc analysis of the subgroup of 46 patients with periphera...

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Bibliographic Details
Published in:Schmerz (Berlin, Germany) Germany), 2017-10, Vol.31 (5), p.524-526
Main Authors: Eitner, L, Vollert, J, Maier, C, Attal, N
Format: Article
Language:ger
Subjects:
Botulinum Toxins, Type A - adverse effects
Botulinum Toxins, Type A - therapeutic use
Double-Blind Method
Injections, Subcutaneous
Neuralgia - drug therapy
Neuralgia, Postherpetic - drug therapy
Pain Measurement - drug effects
Pain, Postoperative - drug therapy
Peripheral Nerve Injuries - drug therapy
Polyneuropathies - drug therapy
Quality of Life
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Summary:The randomized controlled trial (RCT) presented in this article showed significant relief in neuropathic pain following subcutaneous injections of botulinum toxin A over 24 weeks compared to placebo. This result was confirmed in a novel post-hoc analysis of the subgroup of 46 patients with peripheral nerve injury. Relevant adverse effects did not occur during the RCT.
ISSN:1432-2129
DOI:10.1007/s00482-017-0235-9