Effect of Zhuang medicine medicated thread moxibustion on protomics in serum of postherpetic neuralgia patient with Herpes zoster

The aim of this study was to observe the effect of Zhuang medicine medicated thread moxibustion on protomics in serum of postherpetic neuralgia patient with herpes zoster and discuss the action mechanism of Zhuang medicine medicated thread moxibustion in treating postherpetic neuralgia (PHN). Patien...

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Bibliographic Details
Published in:Pakistan journal of pharmaceutical sciences 2017-05, Vol.30 (3(Special)), p.1063-1067
Main Authors: Gang, Fang, Pan, Chen, Haicheng, Wen, Hongrui, Zhang, Jiang, Zhong, Chen, Lin
Format: Article
Language:English
Subjects:
Herpes Zoster - complications
Herpes Zoster - therapy
Humans
Moxibustion
Neuralgia, Postherpetic - blood
Neuralgia, Postherpetic - complications
Neuralgia, Postherpetic - therapy
Pain Measurement
Proteomics
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Summary:The aim of this study was to observe the effect of Zhuang medicine medicated thread moxibustion on protomics in serum of postherpetic neuralgia patient with herpes zoster and discuss the action mechanism of Zhuang medicine medicated thread moxibustion in treating postherpetic neuralgia (PHN). Patients were divided into three groups in clinic, namely the pre-treatment group (n=20), post-treatment group (n=20) and healthy group (n=20), patients meeting corresponding conditions were recruited in the voluntary principle to accept PHN pain evaluation and protomics tests respectively. Compared with the pre-treatment group, visual analogue scale (VAS) in post-treatment group obviously reduced, protomics indexes like MFG-ES, Lymphotoxin beta/TNFSF3, IL-19, Neuritin, NCAM-1/CD56 and PECAM-1/CD31 obviously changed. The Zhuang medicine medicated thread moxibustion can treat the postherpetic neuralgia patient with herpes zoster, its internal mechanism is to possibly change the protomics indexes like MFG-ES, Lymphotoxin beta/TNFSF3, IL-19, Neuritin, NCAM-1/CD56 and PECAM-1/CD31.
ISSN:1011-601X