Effect of Percutaneous Edge-to-edge Repair on Mitral Valve Area and Its Association with Pulmonary Hypertension and Outcomes

Abstract Percutaneous edge-to-edge repair using the MitraClip system causes reduction of mitral valve area (MVA). However, its clinical impact is not fully elucidated. This study assessed the impact of postprocedural MVA reduction on pulmonary hypertension and outcomes. A total of 92 patients with g...

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Bibliographic Details
Published in:The American journal of cardiology 2017-08, Vol.120 (4), p.662-669
Main Authors: Utsunomiya, Hiroto, MD, Itabashi, Yuji, MD, Kobayashi, Sayuki, MD, Rader, Florian, MD, Hussaini, Asma, PA, Makar, Moody, MD, Trento, Alfredo, MD, Siegel, Robert J., MD, Kar, Saibal, MD, Shiota, Takahiro, MD
Format: Article
Language:English
Subjects:
Aged
Blood pressure
Cardiac arrhythmia
Cardiac Catheterization - methods
Cardiology
Cardiovascular
Catheters
Confidence intervals
Discordance
Echocardiography
Echocardiography, Three-Dimensional
Echocardiography, Transesophageal
Female
Fibrillation
Follow-Up Studies
Heart
Heart diseases
Heart Valve Prosthesis Implantation - methods
Humans
Hypertension
Hypertension, Pulmonary - etiology
Hypertension, Pulmonary - physiopathology
Male
Mercury
Mitral valve
Mitral Valve - diagnostic imaging
Mitral Valve - surgery
Mitral Valve Insufficiency - complications
Mitral Valve Insufficiency - diagnosis
Mitral Valve Insufficiency - surgery
Orifices
Patients
Planes
Prognosis
Pulmonary arteries
Pulmonary artery
Pulmonary hypertension
Pulmonary Wedge Pressure
Reduction
Regression analysis
Regurgitation
Repair
Retrospective Studies
Surgery
Therapy
Time Factors
Treatment Outcome
Ultrasonic imaging
Ventricle
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Description
Summary:Abstract Percutaneous edge-to-edge repair using the MitraClip system causes reduction of mitral valve area (MVA). However, its clinical impact is not fully elucidated. This study assessed the impact of postprocedural MVA reduction on pulmonary hypertension and outcomes. A total of 92 patients with grades 3 to 4+ mitral regurgitation (MR) who underwent MitraClip therapy were retrospectively reviewed. Using intraprocedural 3-dimensional transesophageal echocardiography (3DTEE), postprocedural MVA was obtained by 2 optimized planes through the medial and lateral orifices of the repaired valve. MVA was reduced by 60.1% immediately after MitraClip procedure (p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2017.05.036