The effect of oral intake during the immediate pre-colonoscopy time period on volume depletion in patients who receive sodium picosulfate

Sodium picosulfate, used in combination with magnesium oxide and citric acid for bowel cleansing, can result in dehydration. We investigated whether enhanced carbohydrate fluid intake pre-colonoscopy could mitigate this effect. We enrolled 398 elective colonoscopy patients in a prospective, controll...

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Bibliographic Details
Published in:Anaesthesia and intensive care 2017-07, Vol.45 (4), p.485-489
Main Authors: Labuschagne, G. S., Morris, R. W.
Format: Article
Language:English
Subjects:
Anesthesia
Blood pressure
Carbohydrates
Carbohydrates - administration & dosage
Care
Citrates - adverse effects
Colonoscopy
Colonoscopy - methods
Dehydration (Physiology)
Dehydration - prevention & control
Drinking
Electrolytes
Endoscopy
Fluids
Humans
Hydration
Hypotension, Orthostatic - prevention & control
Medical personnel
Middle Aged
Older people
Organometallic Compounds - adverse effects
Patients
Picolines - adverse effects
Preoperative Care
Prospective Studies
Single-Blind Method
Sodium
Systolic blood pressure
Urine
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Summary:Sodium picosulfate, used in combination with magnesium oxide and citric acid for bowel cleansing, can result in dehydration. We investigated whether enhanced carbohydrate fluid intake pre-colonoscopy could mitigate this effect. We enrolled 398 elective colonoscopy patients in a prospective, controlled, single-blinded study. The control group (n=194) fasted routinely (minimum seven hours) whilst the treatment group (n=197) drank 1,200 ml carbohydrate solution leading up to admission (up until two hours pre-colonoscopy). On admission a patient survey was completed, and urine specific gravity obtained. Supine blood pressure and pulse rate were measured, and repeated within three minutes of standing. The carbohydrate group had reduced symptoms and signs of dehydration, including thirst (34% versus 65%, P
ISSN:0310-057X
1448-0271
DOI:10.1177/0310057X1704500412