Poly-energetic and virtual mono-energetic images from a novel dual-layer spectral detector CT: optimization of window settings is crucial to improve subjective image quality in abdominal CT angiographies

• Published in: Abdominal imaging 2018-03, Vol.43 (3), p.742-750
• Main Authors: Doerner, Jonas, Luetkens, Julian A., Iuga, Andra-Iza, Byrtus, Jonathan, Haneder, Stefan, Maintz, David, Hickethier, Tilman
• Format: Article
• Language: English
• Subjects: Abdomen; Computed tomography; Gastroenterology; Hepatology; Image contrast; Image quality; Imaging; Medicine; Medicine & Public Health; Noise; Optimization; Radiology; Regression analysis
• ISSN: 2366-004X; 2366-0058
• DOI: 10.1007/s00261-017-1241-1

Purpose We aimed to determine optimal window settings for poly-energetic (PolyE) and virtual mono-energetic images (MonoE) derived from abdominal angiographic studies on a novel dual-layer spectral detector CT (SDCT) system. Methods From 50 patients, SDCT datasets PolyE and MonoE at 70 and 40 keV levels were reconstructed and best individual window width and level (BI-W/L) manually assessed. Through regression analysis, the so-called optimized individual (OI-W/L) values were obtained. Subjective image quality parameters and vessel diameters were measured to determine influences of different W/L settings. Results Image noise was lower and attenuation and contrast-to-noise ratio were higher in MonoE compared to PolyE (all p  ≤ 0.002). Mean BI-W/L values for PolyE, 70, and 40 keV were 637/284, 647/291, and 1568/691, respectively. Mean OI-W/L values were 631/276, 628/286, and 1516/667, respectively. Compared to standard settings, all adjusted W/L settings varied significantly and yielded higher subjective scoring. No between-group differences were found between manually adjusted and mathematically calculated W/L settings. Conclusion PolyE and MonoE from abdominal angiographic SDCT studies require appropriate W/L settings especially at low energy reconstruction levels. Individual adjustment reaches the best image quality but is time consuming. From our data, predefined W/L settings of 640/280 (PolyE/MonoE 70 keV) and 1570/690 (MonoE 40 keV) as a non-individualized starting point for abdominal angiographic studies from the novel SDCT system are suggested.