Intravenous dexmedetomidine for cesarean delivery and its concentration in colostrum

Highlights • Dexmedetomidine sedation during cesarean delivery under regional anesthesia. • Dexmedetomidine concentration measured in blood and colostrum. • Milk-to-plasma ratio did not exceed 1 in any case. • Relative infant dose was very low. • Undetectable amount of dexmedetomidine in the colostr...

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Published in:International journal of obstetric anesthesia 2017-11, Vol.32, p.28-32
Main Authors: Yoshimura, M, Kunisawa, T, Suno, M, Sugawara, A, Kurosawa, A, Nakanishi, R, Aoki, K, Toriumi, T
Format: Article
Language:English
Subjects:
Administration, Intravenous
Adult
Anesthesia & Perioperative Care
Cesarean Section
Colostrum
Colostrum - metabolism
Dexmedetomidine
Dexmedetomidine - administration & dosage
Dexmedetomidine - pharmacokinetics
Female
Humans
Milk-to-plasma ratio
Obstetrics and Gynecology
Pregnancy
Prospective Studies
Relative infant dose
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container_issue
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container_title International journal of obstetric anesthesia
container_volume 32
creator Yoshimura, M
Kunisawa, T
Suno, M
Sugawara, A
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Nakanishi, R
Aoki, K
Toriumi, T
description Highlights • Dexmedetomidine sedation during cesarean delivery under regional anesthesia. • Dexmedetomidine concentration measured in blood and colostrum. • Milk-to-plasma ratio did not exceed 1 in any case. • Relative infant dose was very low. • Undetectable amount of dexmedetomidine in the colostrum in 24 h.
doi_str_mv 10.1016/j.ijoa.2017.05.002
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source ScienceDirect Journals
subjects Administration, Intravenous
Adult
Anesthesia & Perioperative Care
Cesarean Section
Colostrum
Colostrum - metabolism
Dexmedetomidine
Dexmedetomidine - administration & dosage
Dexmedetomidine - pharmacokinetics
Female
Humans
Milk-to-plasma ratio
Obstetrics and Gynecology
Pregnancy
Prospective Studies
Relative infant dose
title Intravenous dexmedetomidine for cesarean delivery and its concentration in colostrum
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