Assisted reproduction techniques in Latin America: The Latin American Registry, 2014

• Published in: Reproductive biomedicine online 2017-09, Vol.35 (3), p.287-295
• Main Authors: Zegers-Hochschild, Fernando, Schwarze, Juan-Enrique, Crosby, Javier, Musri, Carolina, Urbina, Maria Teresa
• Format: Article
• Language: English
• Subjects: Adult; Assisted reproductive technology; Embryo Transfer - adverse effects; Embryo Transfer - methods; Embryo Transfer - statistics & numerical data; Epidemiology; Female; Humans; Infant, Newborn; IVF–ICSI; Latin America; Latin America - epidemiology; Male; Multiple Birth Offspring - statistics & numerical data; Obstetrics and Gynecology; Perinatal outcome; Pregnancy; Pregnancy Outcome - epidemiology; Pregnancy Rate; Pregnancy, Multiple - statistics & numerical data; Registries; Registry; Reproductive Techniques, Assisted - statistics & numerical data; Twins - statistics & numerical data
• ISSN: 1472-6483; 1472-6491
• DOI: 10.1016/j.rbmo.2017.05.021

Abstract Multinational data on assisted reproduction techniques (IVF and intractytoplasmic sperm injection [ICSI], frozen embryo transfer, oocyte donation, preimplantation genetic diagnosis and fertility preservation) were collected from 159 institutions in 15 Latin American countries. A total of 41.34% of IVF–ICSI cycles were conducted in women aged 35–39 years and 23.35% in women aged 40 years and older. After removing freeze-all cases, delivery rate per oocyte retrieval was 25.05% for ICSI and 27.41% for IVF. Multiple births included 20.78% twins and 0.92% triplets and over. In oocyte donation, twins reached 28.93% and triplets 1.07%. Preterm deliveries reached 16.4% in singletons, 55.02% in twins and 76% in triplets. Perinatal mortality in 18,162 births was 23 per 1000 in singletons, 35 per 1000 in twins, and 36 per 1000 in high-order multiples. Elective single embryo transfer represented 2.63% of fresh transfers, with a 32.15% delivery rate per transfer. Elective double embryo transfer represented 23.74% of transfers, with a 41.03% delivery rate per transfer; 11,373 babies (62.6%) were singletons; 6398 (35.2%) twins, and 391 (2.2%), triplets and more. Given the effect of multiple births on prematurity, morbidity and perinatal mortality, reinforcing the existing trend of reducing the number of embryos transferred is mandatory.