Impact of Chronic Kidney Disease on the Presentation and Outcome of Patients Hospitalized With Atrial Fibrillation: Insights From Qatar

Atrial fibrillation (AF) with coexistent chronic kidney disease (CKD) is poorly described in the literature. We compared the presenting symptoms, clinical characteristics, treatment, and outcome of patients hospitalized with AF with and without CKD in a large clinical registry. Data of patients hosp...

Full description

Saved in:
Bibliographic Details
Published in:Angiology 2018-03, Vol.69 (3), p.212-219
Main Authors: Salim, Imtiaz, Al Suwaidi, Jassim, AlBinali, Hajar A, Singh, Rajvir, Al-Qahtani, Awad, Asaad, Nidal, Salam, Amar M.
Format: Article
Language:English
Subjects:
Aged
Anti-Arrhythmia Agents - therapeutic use
Anticoagulants - therapeutic use
Atrial Fibrillation - complications
Atrial Fibrillation - mortality
Atrial Fibrillation - therapy
Female
Hospital Mortality
Hospitalization
Humans
Male
Middle Aged
Odds Ratio
Qatar
Registries
Renal Insufficiency, Chronic - epidemiology
Retrospective Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Atrial fibrillation (AF) with coexistent chronic kidney disease (CKD) is poorly described in the literature. We compared the presenting symptoms, clinical characteristics, treatment, and outcome of patients hospitalized with AF with and without CKD in a large clinical registry. Data of patients hospitalized with AF between 1991 and 2012 in Qatar were analyzed. Of 5201 patients hospitalized for AF, 264 (5.1%) had CKD. Patients with AF and CKD were older with higher prevalence of other comorbidities and left ventricular dysfunction and were more likely to present with shortness of breath and chest pain compared with patients with AF alone who were more likely to present with palpitation. The crude in-hospital mortality was 3 times higher in patients with dual disease. On multivariable adjustments, CKD was an independent predictor of mortality (odds ratio: 2.84; 95% confidence interval: 1.33-6.08, P = .001). Further studies are warranted to try to reduce the increased mortality observed in this high-risk population.
ISSN:0003-3197
1940-1574
DOI:10.1177/0003319717717849