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Balloon Aortic Valvuloplasty in The Transcatheter Valve Era: Single Centre Indications And Early Safety Data in A High Risk Population
Background The introduction of transcatheter aortic valve implantation (TAVI) has generated a renewed interest in the techniques available to treat high-risk patients with severe aortic stenosis (AS). We report our single centre experience with balloon aortic valvuloplasty (BAV) focussing on indicat...
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Published in: | Heart, lung & circulation lung & circulation, 2018-05, Vol.27 (5), p.595-600 |
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creator | Ford, Thomas J., MBChB Nguyen, Katherine, MBBS Brassil, Joseph, MBBS Kushwaha, Virag, MBBS, PhD Friedman, Daniel, MBBCh Allan, Roger, MBBS Pitney, Mark, MBBS Jepson, Nigel, MBBS |
description | Background The introduction of transcatheter aortic valve implantation (TAVI) has generated a renewed interest in the techniques available to treat high-risk patients with severe aortic stenosis (AS). We report our single centre experience with balloon aortic valvuloplasty (BAV) focussing on indications, procedural success and 30-day outcomes. Methods We retrospectively reviewed all patients that underwent BAV procedures at our institution between August 2012 and August 2014. Procedural success and complications were adjudicated according to VARC-2 criteria. Results Fifty-one consecutive adult patients with severe symptomatic AS underwent a total of 55 BAV procedures. The patients had a mean age of 88 ± 5.7 years and all had extensive comorbidities with a high surgical risk (mean logistic EuroSCORE of 25.22% ± 14.5%). Indications for BAV included palliation of symptoms n = 42 (76%); bridge to definitive valve replacement (n = 6, 11%); and evaluation of response (n = 6, 11%). The procedure was completed in all patients with no intraprocedural deaths (within 24 hours) and low 30-day mortality at 3.9% (n = 2). Minor vascular complications occurred in 11.8% (n = 6), whilst permanent pacemaker implantation was required in 5.8% (n = 3). There were no cases of myocardial infarction, stroke, tamponade, severe aortic regurgitation or major vascular complications during 30-day follow-up. Conclusions Balloon aortic valvuloplasty may be performed safely and effectively with high procedural success and low 30-day complications, even in a very high-risk and elderly cohort of patients in whom the role of TAVI is uncertain or inappropriate. |
doi_str_mv | 10.1016/j.hlc.2017.05.128 |
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We report our single centre experience with balloon aortic valvuloplasty (BAV) focussing on indications, procedural success and 30-day outcomes. Methods We retrospectively reviewed all patients that underwent BAV procedures at our institution between August 2012 and August 2014. Procedural success and complications were adjudicated according to VARC-2 criteria. Results Fifty-one consecutive adult patients with severe symptomatic AS underwent a total of 55 BAV procedures. The patients had a mean age of 88 ± 5.7 years and all had extensive comorbidities with a high surgical risk (mean logistic EuroSCORE of 25.22% ± 14.5%). Indications for BAV included palliation of symptoms n = 42 (76%); bridge to definitive valve replacement (n = 6, 11%); and evaluation of response (n = 6, 11%). The procedure was completed in all patients with no intraprocedural deaths (within 24 hours) and low 30-day mortality at 3.9% (n = 2). Minor vascular complications occurred in 11.8% (n = 6), whilst permanent pacemaker implantation was required in 5.8% (n = 3). There were no cases of myocardial infarction, stroke, tamponade, severe aortic regurgitation or major vascular complications during 30-day follow-up. Conclusions Balloon aortic valvuloplasty may be performed safely and effectively with high procedural success and low 30-day complications, even in a very high-risk and elderly cohort of patients in whom the role of TAVI is uncertain or inappropriate.</description><identifier>ISSN: 1443-9506</identifier><identifier>EISSN: 1444-2892</identifier><identifier>DOI: 10.1016/j.hlc.2017.05.128</identifier><identifier>PMID: 28688833</identifier><language>eng</language><publisher>Australia: Elsevier B.V</publisher><subject>Aortic stenosis ; Balloon aortic valvuloplasty ; Cardiovascular ; Heart failure</subject><ispartof>Heart, lung & circulation, 2018-05, Vol.27 (5), p.595-600</ispartof><rights>Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)</rights><rights>2017 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ)</rights><rights>Copyright © 2017 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-b70466972c68a7f84bb4694531d3fe0cad1002b4332cec27abf0e3b83e8dd6043</citedby><cites>FETCH-LOGICAL-c408t-b70466972c68a7f84bb4694531d3fe0cad1002b4332cec27abf0e3b83e8dd6043</cites><orcidid>0000-0003-4009-6652</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28688833$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ford, Thomas J., MBChB</creatorcontrib><creatorcontrib>Nguyen, Katherine, MBBS</creatorcontrib><creatorcontrib>Brassil, Joseph, MBBS</creatorcontrib><creatorcontrib>Kushwaha, Virag, MBBS, PhD</creatorcontrib><creatorcontrib>Friedman, Daniel, MBBCh</creatorcontrib><creatorcontrib>Allan, Roger, MBBS</creatorcontrib><creatorcontrib>Pitney, Mark, MBBS</creatorcontrib><creatorcontrib>Jepson, Nigel, MBBS</creatorcontrib><title>Balloon Aortic Valvuloplasty in The Transcatheter Valve Era: Single Centre Indications And Early Safety Data in A High Risk Population</title><title>Heart, lung & circulation</title><addtitle>Heart Lung Circ</addtitle><description>Background The introduction of transcatheter aortic valve implantation (TAVI) has generated a renewed interest in the techniques available to treat high-risk patients with severe aortic stenosis (AS). We report our single centre experience with balloon aortic valvuloplasty (BAV) focussing on indications, procedural success and 30-day outcomes. Methods We retrospectively reviewed all patients that underwent BAV procedures at our institution between August 2012 and August 2014. Procedural success and complications were adjudicated according to VARC-2 criteria. Results Fifty-one consecutive adult patients with severe symptomatic AS underwent a total of 55 BAV procedures. The patients had a mean age of 88 ± 5.7 years and all had extensive comorbidities with a high surgical risk (mean logistic EuroSCORE of 25.22% ± 14.5%). Indications for BAV included palliation of symptoms n = 42 (76%); bridge to definitive valve replacement (n = 6, 11%); and evaluation of response (n = 6, 11%). The procedure was completed in all patients with no intraprocedural deaths (within 24 hours) and low 30-day mortality at 3.9% (n = 2). Minor vascular complications occurred in 11.8% (n = 6), whilst permanent pacemaker implantation was required in 5.8% (n = 3). There were no cases of myocardial infarction, stroke, tamponade, severe aortic regurgitation or major vascular complications during 30-day follow-up. Conclusions Balloon aortic valvuloplasty may be performed safely and effectively with high procedural success and low 30-day complications, even in a very high-risk and elderly cohort of patients in whom the role of TAVI is uncertain or inappropriate.</description><subject>Aortic stenosis</subject><subject>Balloon aortic valvuloplasty</subject><subject>Cardiovascular</subject><subject>Heart failure</subject><issn>1443-9506</issn><issn>1444-2892</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp9kc1uEzEURkcIREvhAdggL9lk8N94PCAhhZDSSpVAJLC1PJ47jVPHDvZMpbxAnxtPUliwYHXv4nyfdM8titcElwQT8W5bbpwpKSZ1iauSUPmkOCec8xmVDX163NmsqbA4K16ktMUZ5Kx5XpxRKaSUjJ0XD5-0cyF4NA9xsAb91O5-dGHvdBoOyHq03gBaR-2T0cMGBohHBNAy6vdoZf2tA7QAP0RA176zmbLBJzT3HVrq6A5opXvIVZ_1oKe-Obqytxv03aY79C3sR3cMvCye9dolePU4L4ofl8v14mp28_XL9WJ-MzMcy2HW1pgL0dTUCKnrXvK25aLhFSMd6wEb3RGMacsZowYMrXXbY2CtZCC7TmDOLoq3p959DL9GSIPa2WTAOe0hjEmRhtRCVKxqMkpOqIkhpQi92ke70_GgCFaTfrVVWb-a9Ctcqaw_Z9481o_tDrq_iT--M_DhBEA-8t5CVMlY8AY6G8EMqgv2v_Uf_0kbZ3127u7gAGkbxuizPUVUogqr1fT_6f2kZpg3Tc1-Ax5wqrE</recordid><startdate>20180501</startdate><enddate>20180501</enddate><creator>Ford, Thomas J., MBChB</creator><creator>Nguyen, Katherine, MBBS</creator><creator>Brassil, Joseph, MBBS</creator><creator>Kushwaha, Virag, MBBS, PhD</creator><creator>Friedman, Daniel, MBBCh</creator><creator>Allan, Roger, MBBS</creator><creator>Pitney, Mark, MBBS</creator><creator>Jepson, Nigel, MBBS</creator><general>Elsevier B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4009-6652</orcidid></search><sort><creationdate>20180501</creationdate><title>Balloon Aortic Valvuloplasty in The Transcatheter Valve Era: Single Centre Indications And Early Safety Data in A High Risk Population</title><author>Ford, Thomas J., MBChB ; Nguyen, Katherine, MBBS ; Brassil, Joseph, MBBS ; Kushwaha, Virag, MBBS, PhD ; Friedman, Daniel, MBBCh ; Allan, Roger, MBBS ; Pitney, Mark, MBBS ; Jepson, Nigel, MBBS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-b70466972c68a7f84bb4694531d3fe0cad1002b4332cec27abf0e3b83e8dd6043</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Aortic stenosis</topic><topic>Balloon aortic valvuloplasty</topic><topic>Cardiovascular</topic><topic>Heart failure</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ford, Thomas J., MBChB</creatorcontrib><creatorcontrib>Nguyen, Katherine, MBBS</creatorcontrib><creatorcontrib>Brassil, Joseph, MBBS</creatorcontrib><creatorcontrib>Kushwaha, Virag, MBBS, PhD</creatorcontrib><creatorcontrib>Friedman, Daniel, MBBCh</creatorcontrib><creatorcontrib>Allan, Roger, MBBS</creatorcontrib><creatorcontrib>Pitney, Mark, MBBS</creatorcontrib><creatorcontrib>Jepson, Nigel, MBBS</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Heart, lung & circulation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ford, Thomas J., MBChB</au><au>Nguyen, Katherine, MBBS</au><au>Brassil, Joseph, MBBS</au><au>Kushwaha, Virag, MBBS, PhD</au><au>Friedman, Daniel, MBBCh</au><au>Allan, Roger, MBBS</au><au>Pitney, Mark, MBBS</au><au>Jepson, Nigel, MBBS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Balloon Aortic Valvuloplasty in The Transcatheter Valve Era: Single Centre Indications And Early Safety Data in A High Risk Population</atitle><jtitle>Heart, lung & circulation</jtitle><addtitle>Heart Lung Circ</addtitle><date>2018-05-01</date><risdate>2018</risdate><volume>27</volume><issue>5</issue><spage>595</spage><epage>600</epage><pages>595-600</pages><issn>1443-9506</issn><eissn>1444-2892</eissn><abstract>Background The introduction of transcatheter aortic valve implantation (TAVI) has generated a renewed interest in the techniques available to treat high-risk patients with severe aortic stenosis (AS). We report our single centre experience with balloon aortic valvuloplasty (BAV) focussing on indications, procedural success and 30-day outcomes. Methods We retrospectively reviewed all patients that underwent BAV procedures at our institution between August 2012 and August 2014. Procedural success and complications were adjudicated according to VARC-2 criteria. Results Fifty-one consecutive adult patients with severe symptomatic AS underwent a total of 55 BAV procedures. The patients had a mean age of 88 ± 5.7 years and all had extensive comorbidities with a high surgical risk (mean logistic EuroSCORE of 25.22% ± 14.5%). Indications for BAV included palliation of symptoms n = 42 (76%); bridge to definitive valve replacement (n = 6, 11%); and evaluation of response (n = 6, 11%). The procedure was completed in all patients with no intraprocedural deaths (within 24 hours) and low 30-day mortality at 3.9% (n = 2). Minor vascular complications occurred in 11.8% (n = 6), whilst permanent pacemaker implantation was required in 5.8% (n = 3). There were no cases of myocardial infarction, stroke, tamponade, severe aortic regurgitation or major vascular complications during 30-day follow-up. Conclusions Balloon aortic valvuloplasty may be performed safely and effectively with high procedural success and low 30-day complications, even in a very high-risk and elderly cohort of patients in whom the role of TAVI is uncertain or inappropriate.</abstract><cop>Australia</cop><pub>Elsevier B.V</pub><pmid>28688833</pmid><doi>10.1016/j.hlc.2017.05.128</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-4009-6652</orcidid></addata></record> |
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subjects | Aortic stenosis Balloon aortic valvuloplasty Cardiovascular Heart failure |
title | Balloon Aortic Valvuloplasty in The Transcatheter Valve Era: Single Centre Indications And Early Safety Data in A High Risk Population |
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