Pseudomonas aeruginosa quorum sensing modulates immune responses: An updated review article

•Bacteria use quorum sensing to enhance their survival in the hosts.•Pseudomonas aeruginosa uses LasI/LasR and RhlI/RhlR systems for quorum sensing.•The signaling molecules from the quorum sensing induce/stimulate immune responses.•Pseudomonas aeruginosa uses quorum sensing molecules to attenuate im...

Full description

Saved in:
Bibliographic Details
Published in:Immunology letters 2017-10, Vol.190, p.1-6
Main Authors: Kariminik, Ashraf, Baseri-Salehi, Majid, Kheirkhah, Babak
Format: Article
Language:English
Subjects:
3O-C12-HSL
Animals
Bacterial Proteins - metabolism
C4-HSL
Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit - metabolism
Gene Expression Regulation, Bacterial
Humans
Immune Evasion
Immune system
Immunity, Innate
Pseudomonas aeruginosa
Pseudomonas aeruginosa - immunology
Pseudomonas Infections - immunology
Quorum Sensing
Trans-Activators - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•Bacteria use quorum sensing to enhance their survival in the hosts.•Pseudomonas aeruginosa uses LasI/LasR and RhlI/RhlR systems for quorum sensing.•The signaling molecules from the quorum sensing induce/stimulate immune responses.•Pseudomonas aeruginosa uses quorum sensing molecules to attenuate immune responses. Pseudomonas aeruginosa is an opportunistic bacterium which induces some complications in immunocompromised patients. Pseudomonas aeruginosa is a quorum-sensing using bacterium which regulates its genes expression. The bacterium uses two famous pathways for quorum sensing entitled LasI/LasR and RhlI/RhlR systems. It has been documented that the bacteria which use quorum sensing are able to overcome immune responses. This review article aims to present recent information regarding the effects of Pseudomonas aeruginosa quorum sensing systems on the host immune responses.
ISSN:0165-2478
1879-0542
DOI:10.1016/j.imlet.2017.07.002