Depression, anxiety and stress severities in multiple sclerosis patients using injectable versus oral treatments

Studies on multiple sclerosis in Saudi Arabia remain scant, particularly studies on the psychological aspects. This study measures severities of depression, anxiety and stress, and compares them to the used disease-modifying treatment. Cross-sectional study using a phone questionnaire targeting 452...

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Bibliographic Details
Published in:Journal of comparative effectiveness research 2017-07, Vol.6 (5), p.405-412
Main Authors: Al-Hussain, Fawaz, Al-Salloum, Noura, Alazwary, Naael, Saeedi, Jameelah, Howaidi, Sara, Daif, Abdulkader
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
anxiety
Anxiety - etiology
Cross-Sectional Studies
DASS
depression
Depression - etiology
DMT
Female
fingolimod
Fingolimod Hydrochloride - administration & dosage
Humans
Immunosuppressive Agents - administration & dosage
injections
Injections - adverse effects
Interferon beta-1a - administration & dosage
Interferon beta-1b - administration & dosage
interferons
Male
multiple sclerosis
Multiple Sclerosis, Relapsing-Remitting - drug therapy
Multiple Sclerosis, Relapsing-Remitting - psychology
natalizumab
Natalizumab - administration & dosage
stress
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Summary:Studies on multiple sclerosis in Saudi Arabia remain scant, particularly studies on the psychological aspects. This study measures severities of depression, anxiety and stress, and compares them to the used disease-modifying treatment. Cross-sectional study using a phone questionnaire targeting 452 Saudi patients with relapsing-remitting multiple sclerosis following in King Khalid University Hospital, King Fahad Medical City or Security Forces Hospital. From 235 patients, 149 used interferons, 58 used fingolimod and 28 used natalizumab. Depression scores were similar among all demographic and drug groups. Interferons versus fingolimod anxiety scores were significantly different (p = 0.035). Stress scores were within normal limits. Mild anxiety was higher among interferon users, which could be due to injection anxiety reasons.
ISSN:2042-6305
2042-6313
DOI:10.2217/cer-2016-0087