Comparative Evaluation of Bladder-specific Health-related Quality of Life Instruments for Bladder Cancer

To compare 2 bladder cancer-specific health-related quality of life instruments (HRQOL) in the same patient population. Previous HRQOL studies in cystectomy patients have yielded conflicting results. Using a cross-sectional study design, we examined the only 2 validated bladder cancer-specific (HRQO...

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Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2017-10, Vol.108, p.76-81
Main Authors: Moncrief, Travis J., Balaji, Priya, Lindgren, Bruce B., Weight, Christopher J., Konety, Badrinath R.
Format: Article
Language:English
Subjects:
Aged
Cross-Sectional Studies
Cystectomy - psychology
Female
Health Status
Humans
Male
Middle Aged
Quality of Life - psychology
Retrospective Studies
Surveys and Questionnaires
Urinary Bladder Neoplasms - physiopathology
Urinary Bladder Neoplasms - psychology
Urinary Bladder Neoplasms - surgery
Urination - physiology
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Summary:To compare 2 bladder cancer-specific health-related quality of life instruments (HRQOL) in the same patient population. Previous HRQOL studies in cystectomy patients have yielded conflicting results. Using a cross-sectional study design, we examined the only 2 validated bladder cancer-specific (HRQOL) measures. Of the 256 patients who had undergone radical cystectomy from 2009 to 2014, 131 met both inclusion and exclusion criteria. The Functional Assessment Cancer Therapy-Vanderbilt Cystectomy Index (FACT-VCI) and Bladder Cancer Index (BCI) were mailed to these patients. Overall HRQOL and individual domain scores were compared between the 2 instruments with a Spearman correlation coefficient. HRQOL scores were compared by urinary diversion type as well using a non-parametric Wilcoxon rank sum test. Our study had a response rate of 49% from 31 ileal conduit (IC) and 33 orthotopic neobladder patients. Overall, there was a moderate correlation between the FACT-VCI and BCI surveys (r = 0.57, P 
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2017.06.032