Impact of Cardiorespiratory Fitness and Risk of Systemic Hypertension in Nonobese Versus Obese Men Who Are Metabolically Healthy or Unhealthy

• Published in: The American journal of cardiology 2017-09, Vol.120 (5), p.765-768
• Main Authors: Jae, Sae Young, Babu, Abraham Samuel, Yoon, Eun Sun, Kurl, Sudhir, Laukkanen, Jari A., Choi, Yoon-Ho, Franklin, Barry A.
• Format: Article
• Language: English
• Subjects: Abnormalities; Adult; Age; Aged; Alcohol; Body mass; Body Mass Index; Cardiorespiratory Fitness; Cardiovascular disease; Categories; Cholesterol; Confidence intervals; Diabetes; Exercise; Exercise Therapy - methods; Genotype & phenotype; Glucose; Habitus; Health Status; Humans; Hypertension; Hypertension - epidemiology; Hypertension - etiology; Hypertension - prevention & control; Incidence; Male; Medical prognosis; Medical screening; Men; Mens health; Metabolism; Middle Aged; Obesity; Obesity - complications; Obesity - physiopathology; Oxygen; Oxygen uptake; Phenotype; Physical fitness; Prevalence; Republic of Korea - epidemiology; Retrospective Studies; Risk; Risk Factors; Uric acid; Young Adult
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/j.amjcard.2017.05.054

Few data are available regarding the influence of body phenotype on systemic hypertension (SH) and whether cardiorespiratory fitness (CRF) attenuates this relation. We tested the hypothesis that obesity phenotypes and CRF would predict incident hypertension, evaluating 3,800 Korean men who participated in 2 health examinations in1998 to 2009. All participants were normotensive at baseline and were divided into 4 groups based on body mass index using the Asia-Pacific descriptors for obesity and metabolic health status and the National Cholesterol Education Program's adult treatment panel III (ATP-III) criteria. A metabolically healthy obese (MHO) phenotype was defined as a body mass index of ≥25 kg/m2 with