Near infrared quantum dots in biomedical applications: current status and future perspective

To address the requirements of biomedical applications including biosensing, bioimaging, and drug delivery, fluorescent nanomaterials served as efficient tools in many cases. Among them, near‐infrared quantum dots (NIR QDs) have been used as novel fluorescent labels for their binary advantages of bo...

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Bibliographic Details
Published in:Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology 2018-05, Vol.10 (3), p.e1483-n/a
Main Authors: Zhao, Peng, Xu, Quan, Tao, Jia, Jin, Zongwen, Pan, Yue, Yu, Changmin, Yu, Zhiqiang
Format: Article
Language:English
Subjects:
Animals
Biomedical materials
Biosensors
Diagnostic software
Diagnostic systems
Drug delivery
Drug Delivery Systems
Fluorescence
Fluorescent Dyes
Humans
Medical imaging
Mice
Nanomaterials
Nanoparticles
Nanotechnology
Nanotechnology devices
Quantum Dots
Spectroscopy, Near-Infrared
Theranostic Nanomedicine
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Summary:To address the requirements of biomedical applications including biosensing, bioimaging, and drug delivery, fluorescent nanomaterials served as efficient tools in many cases. Among them, near‐infrared quantum dots (NIR QDs) have been used as novel fluorescent labels for their binary advantages of both QDs and NIR light. In this review, through collecting references in recent 10 years, we have introduced basic structures and properties of NIR QDs and summarized the classification and the related synthetic methods. This review also highlights the functionalization and surface bioconjugation of NIR QDs, and their biomedical applications in biosensing, bioimaging, and drug delivery. This article is categorized under: Diagnostic Tools > Diagnostic Nanodevices Diagnostic Tools > In Vitro Nanoparticle‐Based Sensing Diagnostic Tools > In Vivo Nanodiagnostics and Imaging Extinction coefficient value of water and oxy‐ and deoxyhemoglobin plotted ranging from visible to near‐infrared wavelength.
ISSN:1939-5116
1939-0041
DOI:10.1002/wnan.1483