Pathology of Neuroendocrine Tumours of the Female Genital Tract

Neuroendocrine tumours are uncommon or rare at all sites in the female genital tract. The 2014 World Health Organisation (WHO) Classification of neuroendocrine tumours of the endometrium, cervix, vagina and vulva has been updated with adoption of the terms low-grade neuroendocrine tumour and high-gr...

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Bibliographic Details
Published in:Current oncology reports 2017-09, Vol.19 (9), p.59-59, Article 59
Main Authors: Howitt, Brooke E., Kelly, Paul, McCluggage, W. Glenn
Format: Article
Language:English
Subjects:
Antiretroviral drugs
Carcinoma
Carcinoma, Neuroendocrine - pathology
Cervix
Endometrium
Female
Genital Neoplasms, Female - pathology
Genital tract
Genitalia, Female - pathology
Gynecologic Cancers (NS Reed
Humans
Medicine
Medicine & Public Health
Neuroendocrine tumors
Neuroendocrine Tumors - pathology
Oncology
Section Editor
Topical Collection on Gynecologic Cancers
Tumors
Vagina
Vulva
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Summary:Neuroendocrine tumours are uncommon or rare at all sites in the female genital tract. The 2014 World Health Organisation (WHO) Classification of neuroendocrine tumours of the endometrium, cervix, vagina and vulva has been updated with adoption of the terms low-grade neuroendocrine tumour and high-grade neuroendocrine carcinoma. In the endometrium and cervix, high-grade neoplasms are much more prevalent than low-grade and are more common in the cervix than the corpus. In the ovary, low-grade tumours are more common than high-grade carcinomas and the term carcinoid tumour is still used in WHO 2014. The term ovarian small-cell carcinoma of pulmonary type is included in WHO 2014 for a tumour which in other organs is termed high small-cell neuroendocrine carcinoma. Neuroendocrine tumours at various sites within the female genital tract often occur in association with other neoplasms and more uncommonly in pure form.
ISSN:1523-3790
1534-6269
DOI:10.1007/s11912-017-0617-2