Hypothalamic hamartoma presenting with infantile spasms

Background Hypothalamic hamartomas (HH) generally present with gelastic seizures. It is very unusual for a pediatric patient with HH to present with infantile spasms (IS). Case presentation Here we present a 6-month-old boy diagnosed with IS whose brain magnetic resonance imaging (MRI) showed an 18...

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Bibliographic Details
Published in:Child's nervous system 2017-12, Vol.33 (12), p.2197-2200
Main Authors: Işık, Uğur, Saltık, Sema, Tanrıkulu, Bahattin, Özek, M. Memet
Format: Article
Language:English
Subjects:
Case Report
Diagnosis, Differential
Hamartoma - complications
Hamartoma - diagnostic imaging
Humans
Hypothalamic Diseases - complications
Hypothalamic Diseases - diagnostic imaging
Infant
Male
Medicine
Medicine & Public Health
Neurosciences
Neurosurgery
Spasms, Infantile - complications
Spasms, Infantile - diagnostic imaging
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Summary:Background Hypothalamic hamartomas (HH) generally present with gelastic seizures. It is very unusual for a pediatric patient with HH to present with infantile spasms (IS). Case presentation Here we present a 6-month-old boy diagnosed with IS whose brain magnetic resonance imaging (MRI) showed an 18 × 18 × 16 mm mass in the hypothalamus. His seizures did not respond to antiepileptic treatment with vigabatrin and valproic acid. He had disconnective surgery for HH. Immediately postoperatively, his seizures subsided and he has now been seizure-free for 2 years. Conclusion Although hypothalamic hamartomas generally present with gelastic seizures, they should also be considered in the differential diagnosis of infantile spasms.
ISSN:0256-7040
1433-0350
DOI:10.1007/s00381-017-3559-y