First Reported Case of Donor Related Candida Endophthalmitis after Descemet Membrane Endothelial Keratoplasty

PURPOSETo report the first case of Candida donor to host transmission following descemet membrane endothelial keratoplasty (DMEK). METHODSA retrospective case report. RESULTSA patient underwent uneventful DMEK. Following surgery the donor rim was culture positive for Candida. The patient developed f...

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Bibliographic Details
Published in:The open ophthalmology journal 2017, Vol.11, p.117-121
Main Authors: Thompson, Matthew, Carli, David
Format: Report
Language:English
Online Access:Get full text
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Summary:PURPOSETo report the first case of Candida donor to host transmission following descemet membrane endothelial keratoplasty (DMEK). METHODSA retrospective case report. RESULTSA patient underwent uneventful DMEK. Following surgery the donor rim was culture positive for Candida. The patient developed fungal endophthalmitis that was treated medically with multiple injections of voriconazole and amphotericin. Medical treatment was unable to clear the infection and removal of the donor material was required. Following removal the infection subsided. CONCLUSIONCandida interface keratitis and endophthalmitis can occur following DMEK and may be difficult to treat medically. Early removal of the donor material should be considered.
ISSN:1874-3641
1874-3641
DOI:10.2174/1874364101711010117