Performance characteristics of a high-sensitivity cardiac troponin assay using plasma and whole blood samples

•Using AACC Universal Sample Bank, Pylon assay shown to be second-generation hs-cTn.•>90% of whole blood samples of 505 healthy donors were measurable.•Good correlation/concordance with Abbott hsTnI using suspected AMI patient samples•Assay can measure cTnI in whole blood because red blood cells...

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Bibliographic Details
Published in:Clinical biochemistry 2017-12, Vol.50 (18), p.1249-1252
Main Authors: Li, P., Enea, N.S., Zuk, R., Tan, H., Wu, A.H.B., Jaffe, A.S.
Format: Article
Language:English
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Summary:•Using AACC Universal Sample Bank, Pylon assay shown to be second-generation hs-cTn.•>90% of whole blood samples of 505 healthy donors were measurable.•Good correlation/concordance with Abbott hsTnI using suspected AMI patient samples•Assay can measure cTnI in whole blood because red blood cells do not interact with the Pylon probe.
ISSN:0009-9120
1873-2933
DOI:10.1016/j.clinbiochem.2017.08.002