Bilateral multiple evanescent white dot syndrome

Purpose To present a single case of bilateral multiple evanescent white dot syndrome (MEWDS). Methods A single case with three months of follow-up using imaging studies including fundus color photography (FP), fluorescein angiography (FA), indocyanine green angiography (ICGA), fundus autofluorescenc...

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Bibliographic Details
Published in:International ophthalmology 2018-10, Vol.38 (5), p.2153-2158
Main Authors: Veronese, Chiara, Maiolo, Chiara, Morara, Mariachiara, Armstrong, Grayson W., Ciardella, Antonio P.
Format: Article
Language:English
Subjects:
Angiography
Color photography
Disruption
Eye diseases
Fluorescein
Medical imaging
Medicine
Medicine & Public Health
Ophthalmology
Optical Coherence Tomography
Photo Essay
Tomography
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Summary:Purpose To present a single case of bilateral multiple evanescent white dot syndrome (MEWDS). Methods A single case with three months of follow-up using imaging studies including fundus color photography (FP), fluorescein angiography (FA), indocyanine green angiography (ICGA), fundus autofluorescence (FAF), spectral-domain optical coherence tomography (SD-OCT), en face SD-OCT and optical coherence tomography angiography (OCTA) is presented. Results The patient presented with bilateral MEWDS, ultimately with complete resolution of symptoms. FP revealed foveal granularity and white punctate deep retinal spots, FA found early wreath-like hyperfluorescence, while ICGA showed hypofluorescent dots and spots in the early and late stages. FAF showed areas of hyperautofluorescence. SD-OCT revealed disruption of the ellipsoid zone (EZ) and accumulation of hyperreflective material of variable size and shape. En face SD-OCT demonstrated hyporeflective areas corresponding to areas of EZ disruption as well as hyperreflective dots in the outer nuclear layer. OCTA showed areas of photoreceptor slab black-out corresponding to areas of EZ disruption and light areas of flow void or flow disturbance in the choriocapillaris slab. Conclusions This case represents an unusual case of bilateral MEWDS with complete resolution within three months.
ISSN:0165-5701
1573-2630
DOI:10.1007/s10792-017-0673-5