Patterns of C-reactive protein ratio predicts outcomes in healthcare-associated pneumonia in critically ill patients with cancer

Describe the patterns of C-reactive protein relative changes in response to antibiotic therapy in critically ill cancer patients with healthcare-associated pneumonia (HCAP) and its ability to predict outcome. Secondary analysis of a prospective cohort of critically ill cancer patients with HCAP. CRP...

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Bibliographic Details
Published in:Journal of critical care 2017-12, Vol.42, p.231-237
Main Authors: Rabello, Ligia S.C.F., Póvoa, Pedro, Lapa e Silva, Jose R., Azevedo, Luciano C.P., da Silva Ramos, Fernando Jose, Lisboa, Thiago, Soares, Marcio, Salluh, Jorge I.F.
Format: Article
Language:English
Subjects:
Antibiotics
C-reactive protein
Cancer
Cancer therapies
Comorbidity
Critical care
Drug resistance
Epidemiology
Healthcare-associated pneumonia
Infections
Intensive care unit
Laboratories
Medical diagnosis
Mortality
Multiple organ dysfunction syndrome
Neutropenia
Neutrophils
Outcomes
Pathogens
Patients
Pneumonia
Proteins
Sepsis
Statistical analysis
Ventilators
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Summary:Describe the patterns of C-reactive protein relative changes in response to antibiotic therapy in critically ill cancer patients with healthcare-associated pneumonia (HCAP) and its ability to predict outcome. Secondary analysis of a prospective cohort of critically ill cancer patients with HCAP. CRP was sampled every other day from D0 to D6 of antibiotic therapy. Patients were classified according to an individual pattern of CRP-ratio response: fast – CRP at D4 of therapy was
ISSN:0883-9441
1557-8615
DOI:10.1016/j.jcrc.2017.07.021