Salviae Miltiorrhizae BGE Radix Increases Rat Striatal K super(+)-Stimulated Dopamine Release and Activates the Dopamine Release with Protection Against Hydrogen Peroxide-Induced Injury in Rat Pheochromocytoma PC12 Cells

The present study investigated the effect of the medicinal plant Salviae miltiorrhizae radix (SMR) on dopaminergic neurotransmission in comparison with amphetamine. The effect of SM (0.1 g/ml) on K super(+) (20 mM)-stimulated dopamine (DA) release from rat striatal slices was compared with amphetami...

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Bibliographic Details
Published in:Neurochemical research 2006-01, Vol.31 (1), p.109-120
Main Authors: Chung, Tae-Wook, Koo, Byung-Soo, Kim, Kyeong-Oh, Jeong, Hee-Sang, Kim, Min-Gon, Chung, Kang-Hung, Lee, In-Seon, Kim, Cheorl-Ho
Format: Article
Language:English
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Salviae miltiorrhizae
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Summary:The present study investigated the effect of the medicinal plant Salviae miltiorrhizae radix (SMR) on dopaminergic neurotransmission in comparison with amphetamine. The effect of SM (0.1 g/ml) on K super(+) (20 mM)-stimulated dopamine (DA) release from rat striatal slices was compared with amphetamine (10 super(-4) M). Amphetamine and SMR significantly increased K super(+)-stimulated DA release (P
ISSN:0364-3190
1573-6903
DOI:10.1007/s11064-005-9264-3